The Cyclotron and Radiochemistry Program facility's Clinical Production Laboratory, an ISO7 cleanroom, comprises a laminar air flow (LAF) hood, six mini hot cells, and one dispensing LAF hot cell with manipulators.

Automated radiosynthesis units include:

• FASTlab synthesizer for ¹⁸F-FDG production
• Tracerlab FX(F-N) for production of ¹⁸F nucleophilic-based tracers, e.g. FLT and FMSO
• Tracerlab Fx MeI and Fx M for production of ¹¹C methyl iodide, methyl triflate, and ¹¹C-tracers
• Tracerlab FX C Pro, an automated system for radiosynthesis of 11C-tracers requiring more complex synthesis steps
• Trasis All-In-One (AIO) synthesizer for the synthesis of ¹⁸F-FDOPA
• Other systems are available for production of ¹³N-ammonia and ¹⁵O-gas

The laboratory is designed to follow cGMP guidelines for PET radiopharmaceuticals. Under the direction of the Steering Committee, the CRP files FDA applications for producing human-use radiotracers.

Hot cells for synthesizing radiolabeled PET tracers