Ancillary approvals required 

Ancillary reviews assist the IRB with matters related to research risk, regulatory requirements, and research compliance. Not all studies require ancillary review. In some studies, ancillary review or submission is required to receive final IRB approval. In others, ancillary approval may be required. If ancillary approval is required, documentation of IRB approval cannot be released until all ancillary reviews are completed and received in the eIRB file.

Safety Committees

• Institutional Biosafety Committee (IBC)
• Research involving recombinant or synthetic nucleic acid molecules, infectious agents, biologically derived toxins, or other potentially hazardous biological agents
• Ancillary approval required before final IRB approval
• Subcommittee for Human Use Radiation (SHUR)
• Study includes research procedures involving radiation
• Ancillary approval required before final IRB approval
• Radioactive Drug Research Committee (RDRC)
• Research using radioactive drugs in humans without an Investigational New Drug Application (IND)
• Ancillary approval required before final IRB approval
• Stem Cell Research Oversight Committee (SCRO)
• Research on human embryos, human embryonic stem cells (hESCs), and human induced pluripotent stem cells (iPSCs)
• Ancillary approval required before final IRB approval
• Laser Safety Committee
• Research involving the use of lasers are required to register the laser and receive prior approval
• Ancillary approval required before final IRB approval

Scientific/Ethical Committee

• Protocol Review and Monitoring Committee (PRMC)
  
  • Cancer-related research
  • Ancillary approval required before final IRB approval

Other Institutional Reviews

• Conflict of Interest Committee
  
  • Individuals engaged in research undergo a review to ensure relationships with outside entities do not influence or bias the design, conduct or reporting of research 
  • Review of related financial interest is required before final IRB approval
• Medical Education leadership approval
• Research targeting students/residents as subjects
• Approval required before final IRB approval
• Information Systems Acquisition Committee (ISAC)
• Research proposing use of new information systems and related equipment or software
• Submission required before final IRB approval