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Blocking gene may halt growth of breast cancer cells

 

Shutting down a gene called PRMT5 stopped metastatic estrogen receptor-positive (ER+) breast cancer cells from growing after they acquired resistance to a standard therapy known as CDK4/6 inhibitors, UT Southwestern Medical Center researchers showed in a new study.

Drug targeting clear cell renal cell carcinoma shows promising approach

 

– In a groundbreaking phase one clinical trial led by UT Southwestern Medical Center, a short interfering RNA (siRNA) drug directed to tumor cells, ARO-HIF2, effectively disrupted HIF2α, a key driver of clear cell renal cell carcinoma (ccRCC).

Recruitment underway at O’Donnell School of Public Health to meet industry growth and demand

 

O'Donnell School of Public Health recruits for the 2024-2025 school year.

UT Southwestern scientists discover antiviral immune pathway

 

By focusing on a poxvirus protein, a team led by UT Southwestern Medical Center scientists has discovered an antiviral immune pathway that broadly fights a wide variety of viruses.

Gut microbiome offers clues to disparities in rectal cancer

 

The composition of the gut microbiomes in a group of rectal cancer patients reveals distinct signatures by race, ethnicity, and age of onset, with white Hispanics showing significant presence of one specific bacteria, UT Southwestern Medical Center researchers report.