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Gene-editing nanoparticles correct stem cell mutations in cystic fibrosis models

 

Researchers at UT Southwestern Medical Center developed nanoparticles that successfully edited the disease-causing gene in the lungs of a mouse model of cystic fibrosis (CF), swapping a mutated form for a healthy one that persisted in stem cells. Their findings, reported in Science, could offer hope for people with CF and other debilitating genetic lung diseases.

AccessHope, UT Southwestern Medical Center collaborate to expand cancer expertise access in southern states

 

– AccessHope, LLC, a company changing the way leading-edge cancer expertise is delivered, announced that UT Southwestern Harold C. Simmons Comprehensive Cancer Center will become the seventh National Cancer Institute (NCI)-designated center in the AccessHope network.

Study reveals unexpected mechanism of drug resistance in kidney cancer

 

For nearly two decades, how kidney cancer becomes resistant to rapalog drugs has baffled the scientific community. Now a study by researchers at UT Southwestern Medical Center’s Kidney Cancer Program sheds light.