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Physiology: Advanced Phenotype Capabilities

We offer cutting-edge phenotyping capabilities to provide detailed physiological assessments. This enables precise characterization of patient populations, facilitating personalized management approaches for enhancing the accuracy of clinical trials.

an exam room with multiple computer screens, table, stool, and exercise bike

Tests offered:

  • Cardiopulmonary Exercise Testing (CPET): A comprehensive assessment of cardiovascular and respiratory function performed using a stationary bicycle ergometer. This test measures key parameters such as oxygen uptake, carbon dioxide production, and ventilatory efficiency to evaluate the patient's exercise capacity and identify potential limitations.
  • Electrocardiogram (ECG) Assessment: A non-invasive diagnostic tool that records the electrical activity of the heart using electrodes placed on the patient's chest, arms, and legs. The ECG provides valuable information about heart rhythm, conduction abnormalities, and potential signs of cardiac ischemia or infarction.
  • Resting Echocardiography: A detailed ultrasound examination of the heart performed while the patient is at rest. This imaging modality allows for the assessment of cardiac structure, function, and blood flow, enabling the detection of various cardiovascular abnormalities such as valvular disorders, chamber enlargement, and wall motion abnormalities.
  • Stress Echocardiography: An advanced diagnostic procedure that combines echocardiography with physical stress induced by a recumbent bicycle ergometer. By comparing cardiac function at rest and during exercise, stress echocardiography can identify areas of reduced blood flow, aiding in the diagnosis of coronary artery disease and evaluating the severity of valvular disorders.
  • Point-of-Care Bedside Echocardiography: A focused, real-time ultrasound examination of the heart performed at the patient's bedside. This technique allows for rapid assessment of cardiac function, volume status, and potential complications, guiding immediate management decisions and interventions.

CMRU Physiology lab investigations include variety of applications with 2D and 3D capability as well as cutting edge pulmonary exercise testing with accommodating a multitude of protocols.

2024-2025 CMRU Physiology Lab Investigations

  • ECHO
    • Clinical Echo 2D with Reading
    • Clinical Echo 3D with Reading
    • Stress Echo with reading
    • Clinical Echo 2d with Stress Test and Reading
    • Additional views/ Complex Caseload
  • CPET
    • Cardiopulmonary Exercise Test - CPET
    • Additional views/ Complex Caseload

Core Director

As CMRU’s Echo Core Lab Director, I lead the daily operations and quality assurance of our echocardiography facility, working closely with sonographers and CMRU leadership. My primary responsibilities include conducting and overseeing high-quality, scientific, and reproducible cardiac assessments utilizing advanced techniques such as 2D, 3D, M Mode, color Doppler, and strain imaging to evaluate heart size and function with precision. I implement regular reproducibility testing to ensure rigorous quality control measures. Additionally, I create and validate study-specific databases and develop specialized analysis software. Our team provides expert echocardiographic technical assistance, aligning our services with CMRU's overarching research goals.

Our unit's expertise and services are available to other collaborators and Principal Investigators, supporting critical research initiatives.

We are committed to enhancing research capabilities and contributing to significant advancements in cardiovascular medicine.

Dr. Alvin Chandra wearing a light blue shirt with a dark blue tie standing in the Clements University Hospital lobby

Alvin Chandra, M.D.

CMRU Echo Core Lab

Assistant Professor
Internal Medicine, Cardiology