Research

Researchers within the Cain Center for Bladder Health seek to advance knowledge about and further treatments for chronic urinary tract infections, urinary incontinence, and pelvic floor disorders in our patients.

• Urinary tract infections are the most common bacterial infection in the world, accounting for nearly 25% of all infections in women, and resulting in 250 million infections annually.

Because of antibiotic overuse in medicine, there is a growing prevalence of resistant UTIs that are not susceptible to last-line antibiotic treatments. As a result, there is an emphasis on the need for UTI prevention as the primary method for managing recurrent UTIs.

• Urinary incontinence – involuntary loss of urine – affects more than 51% of adult women in the United States. More than 25 million adult Americans experience temporary or chronic urinary incontinence, including those who suffer from an overactive bladder.
• Pelvic organ prolapse is the descent of any of the pelvic floor organs. Some women develop pelvic floor disorders following childbirth. As women age, pelvic organ prolapse and other pelvic floor disorders become more common. One-third of women in the U.S. can have some pelvic area prolapse issues that affect their quality of life.

Research into these conditions is part of the core mission of the Cain Bladder Center.

If you are interested in research, call 833-494-0670 or email us.

De Nisco/Zimmern Lab

Our research primarily takes place in the De Nisco/Zimmern Lab, a collaboration with UT Dallas. Our research combines access to clinical samples with techniques from fields of molecular microbiology, cell biology, and immunology to discover how both microbe and host contribute to this disease that affects millions of women.