The Clinical Research Program oversees the many clinical studies underway within the Department of Orthopaedic Surgery as part of our commitment to excellence in musculoskeletal care and resident mentoring and development as future clinical investigators.

Here are some of the clinical research studies in the Department:

Alexandra Callan, M.D.

• Evaluation of Outcome Following Orthopaedic Oncology Surgery

Ann Golden, M.D.

• Association Between Hemoglobin A1C and Peri-operative Complications in Elective Hand Surgery
  Co-Investigator(s):  Michael Del Core, M.D. (PGY-4 Resident)

Michael Huo, M.D.

• Total Hip Arthroplasty and Femoral Stem Fixation after Acute Femoral Neck Fractures
• Revisions of Total Hip Replacements
• Total Knee Arthroplasty (TKA) Registry

Michael Khazzam, M.D.

• Cerebral desaturation events in beach chair and lateral decubitus positions during shoulder arthroscopy
• Conventus CAGE^TM PH Post-Approval Observational Data Collection Study
• Acnes in Shoulder Arthroplasty: Is it Isolated to the Skin?
• Tornier Shoulder Outcomes Study
• Anterior Cruciate Ligament Tear: Timing of Surgery and Incidence of Associated Intra-Articular Injuries
• Management of Glenoid Deformity during Shoulder Arthroplasty
• Operative vs. Non-Operative Treatment for Atraumatic Rotator Cuff Tears: A Multicenter Randomized Controlled Pragmatic Trial (ARC)
• IV versus Topical TXA in Primary Reverse Total Shoulder Arthroplasty: A Prospective Randomized Trial
• Pyrocarbon IDE Study
• Effectiveness of Corticosteroid vs Ketorolac Shoulder Injections: A Prospective Double-Blinded Randomized Trial
  Co-Investigator(s): Edward Mulligan, D.P.T.; David Tietze, M.D.
• Subscapularis Integrity and Function Following Anatomic and Reverse Total Shoulder Arthroplasty
• Liposomal Bupivacaine vs. Interscalene Nerve Block for Pain Control after Total Shoulder Arthroplasty: A Randomized Clinical Trial
• Are Smartphone App Goniometers a Suitable Replacement for Conventional Goniometer in Assessing Passive and Active Shoulder Range of Motion?
  Co-Investigator(s): Edward Mulligan, D.P.T.
• Shoulder Sleep Registry

George Liu, D.P.M.

• Radiographic and Clinical Outcomes of Foot and Ankle Operative Intervention/Reconstruction
  Co-Investigator(s): Trapper Lalli, M.D.
• Computed Tomographic (CT) and Radiographic Characterizations of the Human Tibiotalar Joint Co-Investigators: Dr. Daniel Moore and Dr. Gina Sims (Radiologist)
• Evaluation of Clinical and Radiographic Outcome, Assessment, and Complications of Ankle Fractures in Patients with and without Diabetes
  Co-Investigator(s): Dane K. Wukich, M.D.; Katherine Raspovic, D.P.M.; Michael VanPelt, D.P.M.; Trapper Lalli, M.D.; Kshitij Manchanda, M.D. (PGY-4 Resident)
• Assessment of Radiographic Parameters and Clinical Outcomes in Foot and Ankle Trauma

Katherine Raspovic, D.P.M.

• Comparing Health-Related Quality of Life in Patients with Diabetic Foot Disorders using SF12 and PROMIS
  Co-Investigator(s): Dane K. Wukich, M.D.; James Whitfield, D.P.M.; Michael VanPelt, D.P.M.; George Liu, D.P.M.; Lawrence Lavery, D.P.M. (Plastic/Orthopaedic, PM&R); Trapper Lalli, M.D.; Javier La Fontaine, D.P.M. (Plastic Surgery/Orthopaedic, PM&R)

Drew Sanders, M.D.

• Treatment of Femoral Fractures in Trauma Patients
• Analysis of the Effect of the Complications Incurred Following a Traumatic Injury on the Clinical Outcomes in Orthopaedic Trauma Surgical Patients
• A Retrospective Review of Complications Following Operative Fixation of Olecranon Fractures
  Co-Investigator(s): Michael Del Core, M.D. (PGY-4 Resident)
• Femoral Fractures Treated with Operative Fixation: A Retrospective Review of Patients with and without Diabetes Mellitus
  Co-Investigator(s): Stephen Wallace, M.D. (PGY-4 Resident)
• Tibia Shaft Fractures Treated with Intramedullary Nailing: Retrospective Review of Patients with and without Diabetes Mellitus
• The Effect of the Affordable Care Act on Orthopaedic Trauma Patients at a Level One Trauma Center
  Co-Investigator(s): Stephen Gates, M.D. (PGY-4 Resident)
• Results of T-Bar External Fixation of Proximal Tibia Fractures
  Co-Investigator(s): Adam Starr, M.D.
• Prospective Randomized Trial Comparing Two Methods of Closed Reduction for Distal Radius Fractures and the Effect on Success of Closed Management
  Co-Investigator(s): Ann Golden, M.D.
• Does Percutaneous Anterior and Posterior Stabilization Improve Mobilization and Pain in Isolated Young-Burgess Lateral Compresion Type-1 Fractures? A Prospective Randomized Trial
  Co-Investigator(s): Adam Starr, M.D.

Ashoke Sathy, M.D.

• Use of a Novel Tibial Traction Triangle for Reduction of Distal Tibia Shaft Fractures
• Vertically Unstable Pelvic Fractures Fixed with Percutaneous Sacroiliac Screws: Does Transiliac-transsacral Placement Decrease Fixation Failure?
  Co-Investigator(s): Adam Starr, M.D.

Adam Starr, M.D.

• A Model of In-hospital Mortality after Trauma in a Large Level I Trauma Center
• A Retrospective Review of Conservative management of Femoral Head Fractures
  Co-Investigator(s): Michael Del Core, M.D. (PGY-4 Resident)
• Major Extremity Trauma Research Consortium(METRC)

Michael Van Hal, M.D.

• Surgeon Experience: Complication, Operative Times, and Outcomes

Dane K. Wukich, M.D.

• Evaluation of Outcomes Following Orthopaedic Foot and Ankle Surgery Using the American College of Surgeons National Surgical Quality Improvement Program Database
• Comparison of two Anatomic Classification for Diabetic Charcot Neuroarthopathy
  Co-Investigator(s): Katherine Raspovic, D.P.M.; George Liu, D.P.M.; Michael VanPelt, D.P.M.; Trapper Lalli, M.D.; Avneesh Chhabra, M.D. (Radiology/Orthopaedic)
• Identification of the Most Feared Complications of Diabetes in Patients with Diabetic Foot related Complaints
  Co-Investigator(s): Trapper Lalli, M.D.; George Liu, D.P.M.; Katherine Raspovic, D.P.M.; James Whitfield, D.P.M.; Lawrence Lavery, D.P.M. (Plastic/Orthopaedic, PM&R); Javier La Fontaine, D.P.M. (Plastic Surgery/Orthopaedic, PM&R)
• Evaluation of Outcomes Following Foot and Ankle Fractures in Patients with Diabetes
• Prospective Clinical Study of Tri-planar TarsometatarsAL (TMT) ArthroDesls with Early WeiGht-BeariNg after Lapiplasty® ProceDure (ALIGN3D)

Paula Hernandez, Ph.D.

• Changes in Chondrocyte Morphology in Osteoarthritic cartilage (HtrA1)
• Study of Osteonecrosis on Femoral Head