Clinical research opportunities

Dec. 7, 2020

Multiple Sclerosis (MS) research study

Join a MS research study today! We are studying the safety and effects of CNM-Au8 (very small liquid gold particles) on patients with MS. If you are 18 to 55 years old, have been diagnosed with relapsing multiple sclerosis in the past 15 years, and have been on a stable dose of Tysabri for the past six months, you may qualify to participate in this latest MS research study.

Your participation could help provide information that will benefit other people with similar conditions in the future. You may be compensated for your voluntary participation, time, and travel expenses.


Oct. 26, 2020

Participants needed for study on potassium supplement effects on blood pressure

The Hypertension Section of the Cardiology Division at the University of Texas Southwestern Medical Center at Dallas is conducting research to compare the effects of two different types of potassium supplements on patients taking a diuretic for treatment of high blood pressure, called chlorthalidone.

Participants will receive health examination and blood tests at no charge. Study medication is also provided at no cost to the participating subjects. The time required for participation in this study is four to five months. There will be compensation for each subject who participates in the study. We are looking for patients with treated or untreated blood pressure less than 160/100. We are seeking individuals who have no other chronic medical problems such as diabetes, kidney disease, heart or liver disease, moderate or severe acid reflux disease, or chronic diarrhea.

If you are taking blood pressure medications, you will stop them and be put on chlorthalidone. You will have scheduled follow-up visits during the study. If you are interested in this study, please contact (214) 648-5940 for further information. (STU 092015-058)


Participants needed for study on blood pressure and reducing brain damage

The Hypertension Section in the Division of Cardiology at UT Southwestern is conducting research to determine if lowering blood pressure with medication can reduce brain damage. Participants will receive health examinations and blood tests at no charge. Blood pressure medications are also provided at no cost to research participants. We are looking for participants with normal blood pressure and high blood pressure between the ages of 55 and 79 years old who have no history of stroke, dementia, heart or kidney disease, sleep apnea, autoimmune diseases, or carotid stents and stenosis. Time required for participation in this study is six weeks (normal blood pressure) to one year (high blood pressure). Research participants will be compensated.

If you are interested in this study, please contact Danielle Pittman BSN, RN, CEN at 214-648-5940 for further information. (STU 102017-029)


Do you have uncontrolled high blood pressure? This study is for you.

The Hypertension Section in the Division of Cardiology at UT Southwestern is conducting research to determine if the use of a minimally-invasive catheter-based procedure that targets the nerves surrounding the renal arteries can help to bring down the high blood pressure in refractory cases of high blood pressure in patients on at least two anti-hypertensive medications.

Study participants will receive care from the study team, including the procedure and follow-up visits. The team is looking for participants between the ages of 18 and 80 years with high blood pressure above 150/90 mmHg, who have no history of autoimmune diseases, stroke, or heart attack in the last six months, sleep apnea, recurrent kidney stones, and on chronic NSAIDs use. Time required for study is six months to four years. Research participants will be compensated.

If interested in this study, contact sandra.nwani@utsouthwestern.edu Sandra Nwani at 214-648-3612, or visit targetbpglobalstudy.com.


Aug. 8, 2020

Department of Plastic Surgery seeks subjects for acne scar study

The Plastic Surgery Department is conducting a study to evaluate the efficacy of fat grafting in acne scars on the face. Eligible subjects must be healthy men and women between the ages of 18 and 50 with moderate to severe acne scars on the face. Subjects must have no recent aesthetic therapies to the areas and be willing to withhold from any facial treatments outside of the study. The study will consist of a single treatment and 2-4 follow up visits. Analysis will include clinical photography, questionnaires feedback, non-invasive skin measurements and micro-biopsies. Participants will be compensated. To find out more information about this study or to get involved, PSRESEARCH@mednet.swmed.edu the Department of Plastic Surgery Research. (STU2020-0310)


March 9, 2020

Are you taking chlorthalidone for high blood pressure?

The Hypertension Section in the Division of Cardiology at UT Southwestern is conducting research to compare the effects of two different potassium supplements on patients taking chlorthalidone for high blood pressure.

We are looking for patients with treated or untreated blood pressure less than 160/100. Individuals must not have other chronic medical problems such as diabetes, kidney disease, heart or liver disease, moderate or severe acid reflux disease, or chronic diarrhea. Participants taking blood pressure medications will stop and be put on chlorthalidone. Scheduled follow-up visits will occur during the study.

Participants will be compensated and receive health examinations, blood tests, and medications at no charge. The time required for participation in this study is four to five months.

If you are interested in this study, contact (214) 648-5940 for further information.

Can lowering blood pressure reduce brain damage?

The Hypertension Section in the Division of Cardiology at UT Southwestern is conducting research to determine if lowering blood pressure with medication can reduce brain damage.

We are looking for participants with normal blood pressure and high blood pressure between the ages of 55- and 79-years-old who have no history of stroke, dementia, heart or kidney disease, sleep apnea, autoimmune diseases, or carotid stents and stenosis.

Participants will be compensated and receive health examinations, blood tests, and blood pressure medications at no charge. Time required for participation in this study is six weeks (normal blood pressure) to one year (high blood pressure).

If you are interested, contact Danielle Pittman at 214-648-5940 for further information.

Refractory high blood pressure? This may be a study for you!

The Hypertension Section in the Division of Cardiology at UT Southwestern is conducting research to determine if the use of a minimally invasive catheter-based procedure can help bring down high blood pressure in refractory cases of high blood pressure, in patients on at least two anti-hypertensive medications.

Study participants will receive care from the study team, including the procedure and follow-up visits. We are looking for participants between the ages of 18- and 80-years old with high blood pressure above 150/90 mmHg. Participants must not have a history of:

  • Autoimmune diseases
  • Stroke or heart attack in the last six months
  • Sleep apnea
  • Recurrent kidney stones
  • Chronic NSAIDs use

Time required for study is six months to four years. Research participants will be compensated. If you are interested in this study, call 214-648-3612, or sandra.nwani@utsouthwestern.edu Sandra Nwani.


Feb. 25, 2020

Research study for Phelan-McDermid Syndrome in children

Children (3-year-old females, 3- to 6-year-old males) may be able to participate in a study to gain a better understanding of a developmental disorder known as Phelan-McDermid Syndrome. The study involves:

  • A visit to the Center for Autism and Developmental Disabilities/Children's Health
  • Parent questionnaires
  • IQ test
  • EEG
  • Motor movement testing
  • Blood draw

Eligible participants will be compensated for their time. For more information call 214-648-4591, or adrian.avila@utsouthwestern.edu Adrian Avila.


Feb. 12, 2020

Have you been diagnosed with a mood disorder and want to cut back or stop drinking alcohol?

If you experience mood swings, difficulty sleeping, racing thoughts and are often irritable, restless, and easily distracted, you may be eligible for a research study that could help you improve your mood and reduce alcohol use.

Visit the study page for more information, or bipolar@utsouthwestern.edu the study coordinator.


Feb. 11, 2020

Can a simple blood test improve depression treatment?

Help us find out! Center for Depression Research and Clinical Care has a new study to test whether a simple blood test can predict if an individual does better between two antidepressants: escitalopram and bupropion. Medications and study-related procedures are provided at no cost to you. For more information call 214-648-4357, or take this survey to see if you qualify.


Feb. 3, 2020

Do you or does someone you know have sarcoidosis?

Researchers in the Department of Internal Medicine are looking for individuals who are interested in participating in a clinical trial of a FDA-approved medication for sarcoidosis. Participants must be between 18 and 90 years of age with a biopsy-confirmed diagnosis of sarcoidosis for at least one year and taking prednisone. Subjects will be compensated for their time. For more information call 214-648-7875, or fabiola.gianella@UTsouthwestern.edu Fabiola Gianella.


Feb. 3, 2020

Participants sought for sarcoidosis study

Researchers in the Department of Internal Medicine are conducting a clinical trial of an investigational drug in patients with sarcoidosis. Participants must be between 18 and 70 years of age with a biopsy-confirmed diagnosis of pulmonary sarcoidosis for at least six months and taking prednisone. Subjects will be compensated for their time. For more information call 214-648-7875, or fabiola.gianella@UTsouthwestern.edu Fabiola Gianella.


Jan. 27, 2020

Participants sought for bipolar disorder study

The Department of Psychiatry is recruiting individuals who have been diagnosed with bipolar disorder, or are having problems with alcohol, mood swings, difficulty sleeping and racing thoughts, for a research study regarding bipolar disorder that could help improve mood and reduce alcohol use. The following may be provided at no cost to each participant: evaluation, doctor visits, financial compensation, and transportation assistance (bus passes). To learn more about the study, call 214-645-5946, Email Jonathan Stewart, or visit the study website.


Jan. 21, 2020

Seeking participants for blood pressure treatment study

The Hypertension Section in the Division of Cardiology at UTSW is conducting research to compare the effects of two different types of potassium supplements on patients taking chlorthalidone for treatment of high blood pressure. Participants will receive health examination and blood tests at no charge. Study medication is also provided at no cost to the participating subjects. Study will take 4-5 months and there will be compensation for each subject who participates in the study. Researchers are are looking for patients who have treated or untreated blood pressure less than 160/100; and have no other chronic medical problems such as diabetes, kidney disease, heart or liver disease, moderate or severe acid reflux disease, or chronic diarrhea. If you are taking blood pressure medications, you will stop them and be put on chlorthalidone. You will have scheduled follow-up visits during the study. If you are interested in this study, call 214-648-5940.


Jan. 21, 2020

Blood pressure treatment study seeking participants

The Hypertension Section in the Division of Cardiology at UTSW is conducting research to determine if lowering blood pressure with medication can reduce brain damage. Participants will receive health examinations and blood tests at no charge. Blood pressure medications are provided at no cost to research participants. We are looking for participants with normal or high blood pressure, between the ages of 55-79, who have no history of stroke, dementia, heart or kidney disease, sleep apnea, autoimmune diseases, or carotid stents and stenosis. Time required for participation in this study is six weeks (normal blood pressure) to one year (high blood pressure). Research participants will be compensated. If you are interested in this study, please contact Danielle Pittman B.S.N., RN, CEN at 214-648-5940 for further information.


Jan. 17, 2020

Are you feeling depressed or down?

If you are a woman age 18-65 and:

  • Are feeling down or depressed
  • Have lost interest or pleasure in doing things
  • Are ­not currently taking antidepressants

You may be eligible for a research study at UT Southwestern evaluating the effect of a natural supplement for depression. Benefits may include:

  • Study medication and monitoring of your depression symptoms at no cost
  • Compensation and transportation assistance

Contact the Psychoneuroendocrine research group at 214-645-6967 or via Email.


Jan. 17, 2020

Analgesics in the pre-hospital setting: Implications on hemorrhage tolerance (fentanyl)

The Institute for Exercise and Environmental Medicine is currently seeking research subjects for a study examining the effects of different pain medications on blood loss. This study, which is funded by the U.S. Army Medical Research and Materiel Command, is being done to better understand the how the fentanyl (pain medication) will alter the capacity to tolerate a serious injury leading to major blood loss in humans. Requirements to participate:

  • 18-45 years of age
  • Healthy, non-obese (body weight greater than or equal to 143 pounds)
  • English speaking
  • No current or previous cardiac, neurological and/or metabolic illness
  • No current or past history of substance or alcohol abuse

Participation will require three study visits lasting ~13 hours in total. During the study visits, subjects will be given pain medication and participate in a number exams that measure bodily function and pain tolerance. Qualified individuals will be compensated. If you would like more information, contact Ileana Hill, BSN, RN, at 214-345-6502 or via ileanahill@texashealth.org.


Jan. 13, 2020

Do you have uncontrolled high blood pressure? This study is for you

The Hypertension Section in the Division of Cardiology at UTSW is conducting research to determine if the use of a minimally-invasive catheter based procedure that targets the nerves surrounding the renal arteries can help to bring down the high blood pressure in refractory cases of high blood pressure in patients on at least two anti-hypertensive medications.

Study participants will receive care from the study team including the procedure and follow-up visits. The team is looking for participants between the ages of 18-80 years with high blood pressure above 150/90 mmHg, who have no history of autoimmune diseases, stroke or heart attack in the last six months, sleep apnea, recurrent kidney stones and on chronic NSAIDs use. Time required for study is six months to four years. Research participants will be compensated. If interested in this study, contact Sandra Nwani at 214-648-3612 or via sandra.nwani@utsouthwestern.edu, or visit TargetBPGlobalStudy.com.


Jan. 6, 2020

Do you suffer from asthma?

If you have been diagnosed with asthma and are between 40-69 years old, you may be eligible to participate in a study on asthma and cognition. This two-session study will take place at SMU East Campus (by Mockingbird Station) and UT Southwestern Medical Center. You will be compensated for participation. For more information, pne@utsouthwestern.edu or call 214-768-1291. This study is conducted by researchers at UTSW Medical Center, University of Texas at Dallas, and Southern Methodist University.


Dec. 16, 2019

Healthy volunteers needed for hydrocortisone study

Are you between the ages of 18 and 50? Are you physically and psychologically healthy? We are looking for healthy volunteers for a research study to help us investigate if an FDA-approved drug hydrocortisone has an effect on the brain and memory. For more information, please david.martinez@utsouthwestern.edu David Martinez or call 214-645-6965.


Find the right UT Southwestern clinical trial for you or a loved one

UT Southwestern's StudyFinder helps patients and their loved ones find clinical trials or other clinical research opportunities. StudyFinder offers a searchable listing of UTSW studies with information from ClinicalTrials.gov. Users can search by disease category (such as heart and vascular or cancer), keyword, age, and gender. Every clinical trial listed has a phone number and email address to contact for questions or enrollment. Check it out so you can help patients get access to vital clinical trial information. Questions? studyfinder@utsouthwestern.edu or call 214-648-5005.