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Discovery at UT Southwestern

Welcome to the first edition of Discovery at UT Southwestern, a publication featuring our institution's latest developments in basic science and clinical research.

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UT Southwestern investigators are working diligently across the spectrum of biomedical research and clinical care to unravel the complexities of human biology. Their research is central to our mission. Read more in this edition of Discovery at UT Southwestern.

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Beyond Human: How AI is Transforming Basic Science and Clinical Medicine

From uncovering secrets of cellular function to redefining cancer diagnosis and treatment, artificial intelligence research has widespread applications at UT Southwestern. Meanwhile, UT Southwestern’s Clinical Informatics Center is leveraging AI and big data to advance research, patient care, and training.

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Among our key initiatives is an AI-powered real-time location system. This advanced system monitors nearly 1,000 tags daily, which are attached to patients and medical equipment. … By identifying bottlenecks and enabling adaptive scheduling, the initiative represents a quantum leap in mitigating clinical inefficiencies through AI.”

Steve Jiang, Ph.D.Professor and Vice Chair for Digital Health and AI in the Department of Radiation Oncology and Director of the UT Southwestern Medical Artificial Intelligence and Automation Laboratory

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The Dallas Heart Study: Laying the Groundwork for Precision Medicine

The landmark study has resulted in 20 years of data and 230 papers in leading journals – but, more importantly, its detailed participant data documented the feasibility of precision medicine worldwide.

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Collaboration Is Key to Biochemistry Department’s Drug Development Success

Thirty years ago, leadership in the Department of Biochemistry set out to build bridges of collaboration and communication between faculty members and to establish and grow five core facilities. Today, discoveries abound.

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Read the Full 2024 Scientific Report

Discovery at UT Southwestern showcases the impactful work emerging from our laboratories and clinical practice. Within its pages, you will find a report on the promise of neuromodulation for a wide range of psychiatric applications and an update on advances in regenerative medicine, as well as accolades and updates from across UT Southwestern.

We honor Cancer Moonshot Scholar Todd Aguilera, M.D., Ph.D., Assistant Professor of Radiation Oncology and a member of UT Southwestern's Experimental Therapeutics Program in the Harold C. Simmons Comprehensive Cancer Center, along with other award-winning faculty.

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Innovation by the Numbers

5,400+

Clinical trials annually

26

Members National Academy of Sciences

$715M+

In research expenditures in FY23