Microarray and Immune Phenotyping Core

The UT Southwestern Microarray and Immune Phenotyping Core (IPC) facility was established in 2001 and has been providing cutting-edge Microarray and high-throughput biomarker profiling services to hundreds of investigators working on basic and clinical research projects. Microarray  IPC core offers wide variety of services covering genomics and proteomics. We provide centralized access to multiplex biomarker discovery technologies to on-campus as well as off-campus investigators. We offer a broad range of products and services for genomic and proteomic biomarker as listed below. Our team of expert technicians, bioinformaticians and scientists who have decades of experience in the field of genomics and proteomics provide extensive technical and scientific support from experiment design to data analysis. Our mission is to provide our investigators with the best biomarker profiling services to boost the scientific discoveries.

Visit the Microarray & IPC website.

Microarray Core platforms

Autoantigen microarray

Autoantigen microarray

Luminex xMAP® System

Luminex xMAP® System

Dante Gonzalez

Quanterix SIMOA® Assay

NanoString GeoMx®

NanoString GeoMx® Digital Spatial Profiler

Meso Scale Discovery®

Meso Scale Discovery® Electrochemiluminescence

Microarray and IPC core team (from Left to right: Quan Li, Indu Raman, Guangchun Chen, Chengsong Zhu, Mei Yan, Li Wang)

Current Service Provided by the Core

  • Autoantigen Microarray for high-throughput autoantibody profiling
    (Profiling IgG, IgM, IgA and IgE autoantibodies against over hundreds of self-antigens in serum, saliva, and other both fluids)
  • Luminex xMAP® System for multiplex biomarker screening
    27-plex cytokines and chemokines
    40-plex cytokines, chemokines and inflammatory factors
    56-plex cytokines,  chemokines and immune factors
  • Quanterix SIMOA® Assay for Ultra-Sensitive Cytokine and biomarker quantification
    Provides robust quantitative detection of various single and multiplex analytes
    Offers a high degree of precision, accuracy, and reproducibility with < 10% inter- and intra-assay CVs
    Over 50 analytes to choose from including IL-17A, TNF-alpha, IL-23, IP-10, TRAIL, IL-6, IL-10 and IL-12p70, NF-L, Tau, etc.
  • NanoString GeoMx® Digital Spatial Profiler for multiplex spatial profiling of proteins or RNAs suitable on FFPE samples
    nCounter Analysis System for multiplex analysis up to 800 targets
    GeoMx™ DSP System for high-plex protein or RNA GX data
    GeoMx™ DSP Assays for 96 RNA/protein targets from FFPE
  • Meso Scale Discovery® Electrochemiluminescence (MSD-ECL, V-Plex, S-Plex) for quantitative protein biomarker profiling
    Meso Scale Discovery biomarker assays for profiling biomarkers, cell signaling pathways, and other applications.
  • Affymetrix Gene Expression Microarray analysis for mRNA and microRNA
  • Next-Generation Sequencing (NGS) for mRNA-SEQ, microRNA-SEQ
  • Quantitative PCR (QPCR) analysis for quantitative analysis of gene expression, SNP and miRNA.
  • DNA and RNA extraction from tissues, cells and FFPE samples
  • Bioanalyzer analysis for DNA, RNA and protein quantification and QC

Microarray Pricing Services

Autoantigen Microarray for High-Throughput Autoantibody Profiling 
Luminex xMAP® System for Multiplex Biomarker Screening 
Meso Scale Discovery® Electrochemiluminescence (MSD-ECL, V-Plex, S-Plex) for Quantitative Protein Biomarker Profiling 
NanoString GeoMx® Digital Spatial Profiler for Multiplex Spatial Profiling of Proteins or RNAs Suitable on FFPE Samples 
nCounter Analysis System for Multiplex Analysis up to 800 Targets 
Affymetrix Gene Expression Microarray Analysis for mRNA and microRNA 
DNA and RNA Extraction from Tissues, Cells and FFPE Samples 
Bioanalyzer Analysis for DNA, RNA and Protein Quantification and QC 
Quantitative PCR (QPCR) Analysis for Quantitative Analysis of
Gene Expression, SNP and miRNA 
Quanterix SIMOA® Assay for Ultra-Sensitive Cytokine and Biomarker Quantification 
Next-Generation Sequencing (NGS) microRNA-SEQv