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2024 Article Archive

How gut bacteria become ‘persisters’ to avoid antibiotics

 

A subpopulation of gut bacteria given a commonly used antibiotic became “persisters” that were able to survive without developing true resistance, UT Southwestern Medical Center scientists discovered.

UT Southwestern finds genetic clues to complex infections

 

Treating complex bacterial infections with customized therapies tailored to the infection and the patient is closer to reality, thanks to researchers at UT Southwestern Medical Center.

UT Southwestern study shows glucagon is key for kidney health

 

Glucagon, a hormone best known for promoting blood sugar production in the liver, also appears to play a key role in maintaining kidney health.

Age, sex, race among top risk factors for revision knee surgery

 

Patients who are younger than about 40, male, or Black are among those most at risk for revision surgery after having had a total knee replacement, according to researchers at UT Southwestern Medical Center.

Experimental compound kills cancer, spares immune cells

 

UT Southwestern Medical Center researchers have identified a compound that selectively eliminates cancer cells while sparing immune cells in a form of cell death known as ferroptosis.

In Memoriam: Jonathan W. Uhr, M.D., renowned immunologist and longtime Chair of Microbiology

 

In Memoriam: Jonathan W. Uhr, M.D., renowned immunologist and longtime Chair of Microbiology

Magnetic fields kill bacteria that infect medical implants

 

UT Southwestern Medical Center is collaborating with Pfizer Inc. to develop RNA enhanced delivery technologies for genetic medicine therapies through the Dallas-based medical center’s Program in Genetic Drug Engineering.

Two Texas transplant programs team up to save lives

 

Two hard-to-match transplant patients 250 miles apart are starting 2024 on a new path to healthy lives. That’s because UT Southwestern Medical Center’s Solid Organ Transplant Program and University Health Transplant Institute in San Antonio searched beyond their own institutional networks to identify compatible living kidney donors for their failing patients.

Gold nanoparticles reverse brain deficits in multiple sclerosis, Parkinson’s

 

Results from phase two clinical trials at UT Southwestern Medical Center showed that a suspension of gold nanocrystals taken daily by patients with multiple sclerosis (MS) and Parkinson’s disease (PD) significantly reversed deficits of metabolites linked to energy activity in the brain and resulted in functional improvements.

UT Southwestern collaborates with Pfizer to develop improved RNA delivery technologies

 

UT Southwestern Medical Center is collaborating with Pfizer Inc. to develop RNA enhanced delivery technologies for genetic medicine therapies through the Dallas-based medical center’s Program in Genetic Drug Engineering.