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Children’s Research Institute at UT Southwestern scientists discover ancient viral DNA activates blood cell production during pregnancy, after bleeding

 

Ancient viral remnants in the human genome are activated during pregnancy and after significant bleeding in order to increase blood cell production, an important step toward defining the purpose of “junk DNA” in humans, according to new research from Children’s Medical Center Research Institute at UT Southwestern (CRI) published in Science.

Children’s Research Institute at UT Southwestern scientist awarded NIH Director’s New Innovator Award

 

Javier Garcia Bermudez, Ph.D., an Assistant Professor in Children’s Medical Center Research Institute at UT Southwestern (CRI), is one of 67 scientists awarded a 2024 National Institutes of Health High-Risk, High-Reward Research grant.

Children’s Health and UT Southwestern break ground on new Dallas pediatric campus, announce $100 million donation from The Rees-Jones Foundation

 

Groundbreaking and donation for the $5 billion campus marks new era of transformative pediatric care in North Texas and beyond.

Children’s Medical Center Dallas seeks community participation in trauma research study to investigate treatment strategies for critically injured children

 

Bleeding is the most common cause of preventable death after injury. Researchers at Children’s Medical Center Dallas are seeking community consultation for possible future participation from parents and legal guardians in a study that will compare two resuscitation treatments (whole blood versus traditional blood component therapy, and tranexamic acid versus no tranexamic acid) for children ages 1 month to 18 years old.

UTSW’s Simmons Cancer Center awarded more than $11.5 million in CPRIT funding

 

Eight scientists and physicians in the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern have been awarded more than $11.5 million in grants from the Cancer Prevention and Research Institute of Texas (CPRIT) to support the state’s fight against cancer.

$25 million donation from Hamon Charitable Foundation will help UT Southwestern, Children’s Health develop joint pediatric campus

 

UT Southwestern Medical Center and Children's HealthSM announced a $25 million gift from the Hamon Charitable Foundation in support of the $5 billion transformative pediatric campus to be built in Dallas’ Southwestern Medical District across from UTSW’s William P. Clements Jr. University Hospital.

Children’s Research Institute at UT Southwestern scientists discover kidney cancers rely on mitochondrial metabolism to metastasize

 

Contrary to how tumors operate while still in the kidney, metastatic kidney cancers rely heavily on mitochondrial metabolism, according to new research from Children’s Medical Center Research Institute at UT Southwestern (CRI) published in Nature.

Natural grass may pose greater risk for football concussions

 

Young football players who sustained a head-to-ground concussion practicing or playing games on natural grass experienced more symptoms – and significantly higher severity – than those who suffered concussions on artificial turf, researchers at UT Southwestern Medical Center found.

Targeting protein has potential to treat leukemia, lymphoma

 

Targeting a protein called ZFP574 suppressed leukemia in a mouse model of the disease, UT Southwestern Medical Center researchers showed in a new study.

Liver cancer growth tied to tryptophan intake

 

Researchers at UT Southwestern Medical Center have discovered that a diet free of the amino acid tryptophan can effectively halt the growth of liver cancer in mice. Their findings, published in Nature Communications, offer new insights for dietary-based cancer treatments and highlight the critical role of the tryptophan metabolite indole 3-pyruvate in liver tumor development.