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Gina R. Poe, Ph.D., speaks as the Carole Mendelson, Ph.D. Distinguished Visiting Professor at the annual event sponsored by the Women in Science and Medicine Advisory Committee.

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Endocrine Glands and the General Principles of Hormone Action Cai Li, Ph.D. Assistant professor Touchstone Center for Diabetes Research Departments of Physiology and Internal Medicine The University of Texas Southwestern Medical Center Dallas, TX 75390-8854 April 6, 2002 “Classical” Endocrine Glands A more complete listing of the endocrine glands Endocrine gland Major hormones Primary target organs Adipose tissue Leptin hypothalamus Adrenal cortex Glucocorticoids liver, muscle

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© 2008 UT Southwestern Medical Center at Dallas Concise Health Risk Tracking (CHRT) with Clinician Rated Behavioral Module Please rate the extent to which each of the following statements describes how you have been feeling or acting in the past week. For example, if you feel the statement very accurately describes how you have been feeling in the past week, you would give a rating of “Strongly Agree.” If you feel the statement is not at all how you have been feeling in the past week

Clinical Aspects of Hyponatremia & Hypernatremia Case Presentation: History 62 y/o male is admitted to the hospital with a 3 month history of excessive urination (polyuria) and excess water intake up to a gallon per day. His wife noted that he had lost weight, became forgetful and irascible. Case Presentation: Physical Examination Emaciated, somnolent 62 y/o man in no acute distress. Multiple signs of dehydration were evident including low blood pressure upon standing (orthostatic

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Anti-malarial Drug Discovery Jeffrey Baldwin, PhD UT Southwestern Medical Center Department of Pharmacology Malaria Burden Life Cycle Jones & Good, Nature Medicine (Feb. 2006) Complex life cycle Intracellular parasite Pathogenesis 4 Plasmodium species are human pathogens: Falciparum Vivax Ovale Malariae Miller et al, Nature (7 Feb, 2002) Clinical Outcomes Miller et al, Nature (7 Feb, 2002) Immune Evasion PfEMP1 is key to lethality of P. falciparum Sticky molecules evade

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