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• Scan in photos of orcas feeding on great whales • Know there are lots of orcas in the north Pacific A Life without Oxygen: The Physiology of Marine Mammals <Picture> COMPETITION FOR RESOURCES How marine mammals do what they do! Dive Response • Stop Breathing • ↓ Cardiac Output • ↓ Peripheral Blood Flow • Lungs Collapse below 60m • But Maintain Aerobic Metabolism Adaptations to Maintain Aerobic Metabolism under Hypoxic

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ß-Lapachone, a ‘Kiss of death’ therapy for cancer David A. Boothman, Ph.D. Laboratory of Molecular Stress Responses Program in Cell Stress and Cancer Nanomedicine Simmons Comprehensive Cancer Center University of Texas Southwestern Medical Center at Dallas September 14, 2008 Cellular Damage New Gene Expression Exploitable Target: Expressed in Human Tumors, not (or low) in Normal Tissues Bioactivate Drug For Tumor-Selective Killing -Not cell cycle

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1 Cancer Cancer NanomedicineNanomedicine JinmingJinming GaoGao, Ph.D., Ph.D. Department of PharmacologyDepartment of Pharmacology Harold C. Simmons Comprehensive Cancer CenterHarold C. Simmons Comprehensive Cancer Center UT Southwestern Medical CenterUT Southwestern Medical Center Departments of Chemistry and BioengineeringDepartments of Chemistry and Bioengineering UT DallasUT Dallas 12,75612,756 kmkm NanomedicineNanomedicine in in PerspectivePerspective Mother EarthMother Earth 25.4

TRAVEL AUTHORIZATION CHECKLIST Before Travel 1. Returned completed and signed Intent to Travel. Yes No 2. Address is current in PeopleSoft. Yes No. If not, please update it in the system. 3. Airline No American United Other _______________ 4. Hotel No In State Name: ____________________________________ (Get state tax exemption information form to take with you.) Out of State Name: __________________________________ 5. Registration

The Skeletal Response to Aging: There’s No Bones About It! April 7, 2001 Joseph E. Zerwekh, Ph.D. Interrelationship of Intestinal, Skeletal, and Renal Systems to the Overall Maintenance of Normal Calcium Homeostasis Blood Calcium Absorption (500 mg) Secretion (300 mg) Resorption (500 mg) Formation (500 mg) Filtration (8000 mg/d) Reabsorption (7800 mg/d) Dietary Ca (800 mg/d) in stool 200 mg lost in urine 600 mg lost 800 mg output Functions of the Human Skeleton • Protects

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How is the brain influenced by radiation? Amelia J. Eisch, Ph.D. Department of Psychiatry, UT Southwestern October 3, 2009 Presenter Presentation Notes Here I will review the efforts of my laboratory, the dept of psychiatry in general, and the larger stem cell community at UT Southwestern to move from correlative to causative studies. Novel mouse model, unpublished and recently published data, movies of how we model these disorders in laboratory animals. Fike, Limoli, and Raber Why does

Representative timeline for a Molecular Biophysics PhD Year Term Half/ Full Title Credit Hour Total Credit Hrs/Term First Year Fall Full Core Curriculum - Proteins 2 Semester Total: 10 Core Curriculum - Genes 2 Core Curriculum- Cell 2 Professionalism, Responsible Conduct of Research, and Ethics I 1 Laboratory Rotations 3 Spring 1st Half Macromolecule I: Energetic Foundation 2 Semester Total: 11 Modern Methods in