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Macromolecules and Metabolism (MM) Course Directors: Dr. Jennifer Kohler and Dr. Andrew Lemoff Grading: • Final Exam: 50% • Quiz: 20% • Online Problem Sets (4): 6% each • Active Learning Sessions (2): 2% each • Completion of course evaluation: 2% **A cumulative weighted score of ≥ 70% correct for all�graded activities will be counted as a��� passing grade. Students must also score at least a 70% on their final exam in order to pass this course. Calendar: 8/5 to 8/30 (first 4 weeks of

M E D I C I N E 2005 Annual Review The Magazine of The University of Texas Southwestern Medical Center > T H E D R E A M O F U N D E R S T A N D I N G S L E E P > L O O K I N G I N S I D E T H E B O D Y > A L Z H E I M E R ’ S D I S C O V E R I E S > A N E W S H A P E A L S O I N S I D E : > C A N C E R P R E V E N T I O N > C L I N I C A L F R O N T I E R HEART AND MIND 2 Researchers and clinicians of UT Southwestern Medical Center’s Alzheimer’s Disease Center are

2 014 A N N U A L R E V I E W The Future of Medicine Has a New Home 2 Stories by Jeanne Forbis, Alfred Marucci, Remekca Owens, Russell Rian, Gregg Shields, and Lisa Warshaw On December 6, 2014, UT Southwestern Medical Center opened the innovative William P. Clements Jr. University Hospital, setting a new standard and era in patient care. Boundless Generosity 28 Story by Russell Rian and Lori Soderbergh �e extraordinary support of the late Harold C. Simmons – an

S O U T H W E S T E R N M E D I C I N E 54 HEN DR. STEVEN MCKNIGHT and his protégé, Dr. Andrew Pieper, set off on their own research expedition at UT Southwestern Medical Center several years ago, they knew they might never arrive at their destination. They were seeking whether there was a way to enhance the birth or survival of newly formed nerve cells in the adult brain. It was an undertaking that could have profound payoffs. If successful, the research could ultimately lead

Mo m e n t s of D i scovery A Journey to the 2011 Nobel Prize VOLUME 21 / NUMBER 1 / FEBRUARY 2012 Southwestern Medicine is a publication of the University News Bureau at The University of Texas Southwestern Medical Center, a component of The University of Texas System. Copyright, 2012, UT Southwestern Medical Center. For permission to quote or reprint any material written herein, for permission to reproduce art, or to request additional copies, please contact the University News

Community investment fuels research to tackle the deadliest breast cancers.

Immerse yourself in opportunities to reconnect with colleagues and celebrate UT Southwestern's momentum.

Join UT Southwestern Medical Center for a reception during the American College of Emergency Physicians 2024 Scientific Assembly.

UT Southwestern celebrated its annual Martin Luther King Commemorative Celebration.

CLINICAL CANCER RESEARCH | CLINICAL TRIALS: TARGETED THERAPY A First-in-Human Phase 1 Study of a Tumor-Directed RNA-Interference Drug against HIF2a in Patients with Advanced Clear Cell Renal Cell Carcinoma James Brugarolas1, Gregory Obara2, Kathryn E. Beckermann3, Brian Rini3, Elaine T. Lam4, James Hamilton5, Thomas Schluep5, Min Yi5, So Wong5, Zhongping Lily Mao5, Erick Gamelin6, and Nizar M. Tannir7 ABSTRACT ◥ Purpose: ARO-HIF2 is an siRNA drug designed to selectively target hypoxia