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Delivering genetic material tagged with a cellular “ZIP code” prompted cells to secrete proteins or drugs into the bloodstream that successfully treated psoriasis and cancer in mouse models, UT Southwestern Medical Center scientists report in a new study.

UT Southwestern researchers identified a previously unknown bacteria-killing protein on the epidermis that requires the vitamin to work.

UT Southwestern Medical Center is the No. 1 hospital in Dallas-Fort Worth – the nation’s fourth-largest metro area – and ranks among the top 50 hospitals nationally in 10 specialties ranging from brain to heart care.

A new tool called PHOTON, developed by scientists at UT Southwestern Medical Center, can identify RNA molecules at their native locations within cells – providing valuable clues to where different RNA species are distributed spatially in response to various cellular cues.

Survival rates for out-of-hospital cardiac arrest (OHCA) fell during the early years of the COVID-19 pandemic, with Black and Hispanic patients experiencing larger decreases in survival, according to a study by UT Southwestern Medical Center researchers published in Resuscitation.

Review of 25,000 patients shows primary care doctors can detect, treat most cases with online help

In work that could someday improve treatments for epilepsy, UT Southwestern scientists have published the first three-dimensional structure of a member of a large family of human proteins that carry charged particles – ions – across the cell membrane.

Kidney damage that seemingly heals appears to mutate the DNA in the mitochondria of kidney cells, making the organ less resilient to future stressors and reducing its function over time, a study led by UT Southwestern Medical Center researchers shows.

UT Southwestern researchers have identified two proteins that act as gatekeepers to dampen a potentially life-threatening immune response to chronic infection.

The increasing sophistication of cancer treatments threatens to outpace the ability of health care providers to enroll patients in clinical trials to test those therapies.