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– In a groundbreaking phase one clinical trial led by UT Southwestern Medical Center, a short interfering RNA (siRNA) drug directed to tumor cells, ARO-HIF2, effectively disrupted HIF2α, a key driver of clear cell renal cell carcinoma (ccRCC).

UT Southwestern scientists have developed a genetically engineered mouse and imaging system that lets them visualize fluctuations in the circadian clocks of cell types in mice.

Delivering genetic material tagged with a cellular “ZIP code” prompted cells to secrete proteins or drugs into the bloodstream that successfully treated psoriasis and cancer in mouse models, UT Southwestern Medical Center scientists report in a new study.

In Memoriam: Jonathan W. Uhr, M.D., renowned immunologist and longtime Chair of Microbiology

Two genes working in tandem play a critical role in shaping the identity and behavior of prostate cancer cells and their response to treatment, UT Southwestern Medical Center researchers report.

The number of mutations in the DNA of cancerous tumors may not be an indicator of how well patients will respond to immune checkpoint inhibitors (ICIs), a commonly prescribed type of immunotherapy, a team led by UT Southwestern Medical Center reported in a retrospective study.

At exactly 11 a.m. Friday, surrounded by family, friends, and mentors, 224 members of UT Southwestern Medical School’s Class of 2024 – who all embarked on their medical education during the height of the COVID-19 pandemic – learned where they will continue their medical training.

Slipping on ice or tripping over a curb can result in broken bones or more serious injuries. To avoid taking an unexpected tumble, it’s important to be aware of your surroundings and watch where you’re walking, a UT Southwestern Medical Center orthopedist advises.

Nearly 100% of UT Southwestern Medical School students matched to residency programs – well above the national average of 94%.

Benjamin Tu, Ph.D., a professor of biochemistry at UT Southwestern whose basic science research into cellular function could lead to greater understanding of diseases including cancer, has been named a recipient of the 2021 Edith and Peter O’Donnell Award in Science, presented by The Academy of