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A new approach that targets the cellular machinery that viruses need to reproduce – rather than the virus itself – appears to stem replication of a common childhood pathogen known as respiratory syncytial virus (RSV), UT Southwestern researchers report in a new study.

Mechanical hearts spur some regeneration in dormant parts of failing hearts, according to a UT Southwestern pilot study that shows promise for developing regenerative heart therapies.

UT Southwestern researchers report the first structural confirmation that endogenous – or self-made – molecules can set off innate immunity in mammals via a pair of immune cell proteins called the TLR4-MD-2 receptor complex.

Funded by a Specialized Program of Research Excellence (SPORE) award from the National Cancer Institute (NCI), the Kidney Cancer Program (KCP) at UT Southwestern’s Harold C. Simmons Comprehensive Cancer Center reports the largest and most diverse catalog of kidney cancer tumor models to date.

Stroke patients on long-term blood thinners who were given the clot-busting drug alteplase enjoyed better recoveries than those who did not receive the drug and had no increased risk of bleeding, a new study led by UTSW researchers shows.

UT Southwestern Medical Center is pleased to announce a $100 million gift from the O’Donnell Foundation to endow and support its new School of Public Health. This investment is the largest gift to a school of public health at a public university in the U.S. and matches the third largest gift

The U.S. Food & Drug Administration has expanded the approved use of belzutifan for treatment of metastatic kidney cancer, another milestone for the novel, first-in-class kidney cancer drug arising from scientific discoveries at UT Southwestern Medical Center.

A first-in-kind immune-modulating drug that arose from decades of basic research at UT Southwestern Medical Center has received approval from the U.S. Food and Drug Administration as a new treatment for myasthenia gravis.

A protein produced by the human immune system can potently inhibit several coronaviruses, including the one behind the current COVID-19 outbreak, an international team of investigators reports today.

Mandatory participation in high school science fairs is counterproductive, emphasizes winning over learning, and sometimes leads to cheating and other research misconduct.