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Scientists have discovered tumors can tap a nontraditional pathway to acquire lipoproteins – molecules that transport fat in blood – which enriches cancer cells with an antioxidant shield to survive stress, according to new research from Children’s Medical Center Research Institute at UT

The dominant form of heart failure worldwide appears to be caused by a strong, bidirectional interaction between the body’s response to metabolic stress and the immune system, according to a review article written by UT Southwestern researchers and colleagues.

UT Southwestern Medical Center scientists have identified the first two cases of the B.1.617.2 (Indian origin) variant of COVID-19 infection in North Texas using next-generation sequencing technologies along with targeted PCR testing.

For the third year in a row, UT Southwestern is ranked as the top health care institution globally by Nature Index for publishing high-quality research in all subjects and in the life sciences.

A new study by UT Southwestern’s Simmons Cancer Center scientists suggests that lactate, a metabolic byproduct produced by cells during strenuous exercise, can rejuvenate immune cells that fight cancer.

Blocking the inhibition of PKD1 and PKD2 gene expression by deleting a binding site for microRNAs hindered the formation and growth of kidney cysts in autosomal dominant polycystic kidney disease (ADPKD) models, UT Southwestern researchers reported.

An international panel of experts from four renowned diabetes research centers, including UT Southwestern Medical Center, has reviewed current literature and is recommending a pivotal change in treatment of Type 2 diabetes to focus on obesity first and glucose control second.

The Centers for Medicare & Medicaid Services (CMS) announced that the Southwestern Health Resources Accountable Care Network (SWHR) saved more than $37 million in 2018.

Funded by a Specialized Program of Research Excellence (SPORE) award from the National Cancer Institute (NCI), the Kidney Cancer Program (KCP) at UT Southwestern’s Harold C. Simmons Comprehensive Cancer Center reports the largest and most diverse catalog of kidney cancer tumor models to date.

A UT Southwestern research team has catalogued gene activity in the skeletal muscle of mice, comparing healthy animals to those carrying a genetic mutation that causes Duchene muscular dystrophy (DMD) in humans.