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A mutation in the gene that causes cystic fibrosis may accelerate heart function decline in those with Duchenne muscular dystrophy (DMD), a new study by UT Southwestern researchers suggests.

In an animal model of multiple sclerosis (MS), decreasing the amount of a protein made in the liver significantly protected against development of the disease’s characteristic symptoms and promoted recovery in symptomatic animals, UTSW scientists report.

A healthy diet, regular exercise, and sufficient sleep can help prevent the onset of diabetes, a condition affecting more than 37 million Americans, according to Bethany Agusala, M.D., Assistant Professor of Internal Medicine at UT Southwestern.

In Memoriam: David J. Mangelsdorf, Ph.D., pioneer in orphan nuclear receptor research and Chair of Pharmacology Published on: August 09, 2025 • By: Newsroom Share Share on Facebook Share on Twitter Share on LinkedIn Email this page Print this page DALLAS – Aug. 9, 2025 – David J. Mangelsdorf, Ph.D., Chair and Professor of Pharmacology at UT Southwestern Medical Center, a visionary scientist who pioneered the once-obscure realm of orphan nuclear receptors (a class of proteins involved in gene

Millions of Americans have chronic shoulder pain, which can have a significant impact on quality of life. Although some get relief from medications, physical therapy, or joint injections, those with persistent pain often pursue more aggressive treatments such as surgeries and permanent

Researchers at UT Southwestern Medical Center have discovered how a hormone interacts with a receptor on the surface of immune cells to shield cancer cells from the body’s natural defenses. The findings, published in Nature Immunology, could lead to new immunotherapy approaches for treating cancer

Revised DFW model shows a dramatic spike in DFW hospitalizations related to COVID, predicting a potential 20% surge over the next two weeks.

Ground has been broken for construction of a new building that will catalyze a unique partnership between UT Southwestern Medical Center and UT Dallas, bringing their biomedical engineering programs together to foster innovative solutions for unmet medical needs.

Essential tremor (ET) is a common movement disorder affecting about 2% of the American population, and more than 20% of those over 90 years old. Despite its prevalence and decades of study, researchers don’t know the precise mechanisms underlying ET.

Contrary to how tumors operate while still in the kidney, metastatic kidney cancers rely heavily on mitochondrial metabolism, according to new research from Children’s Medical Center Research Institute at UT Southwestern (CRI) published in Nature.