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Scar-like cells that make up a sizable portion of malignant pancreatic tumors and shield these cancers from immune attack are derived from mesothelial cells that line tissues and organs, a new study led by UT Southwestern researchers suggests.

Stroke patients on long-term blood thinners who were given the clot-busting drug alteplase enjoyed better recoveries than those who did not receive the drug and had no increased risk of bleeding, a new study led by UTSW researchers shows.

Women who were pregnant during the recent Omicron surge were diagnosed with COVID-19 at a much higher rate than during previous phases of the pandemic, but were less likely to develop severe illness, a study by UT Southwestern and Parkland Health scientists found.

A first-in-kind immune-modulating drug that arose from decades of basic research at UT Southwestern Medical Center has received approval from the U.S. Food and Drug Administration as a new treatment for myasthenia gravis.

W.A. “Tex” Moncrief Jr., whose extraordinary generosity has and will benefit many generations of Texans by expanding UT Southwestern Medical Center programs in Dallas and especially Fort Worth, as well as surrounding communities, died Dec. 28 at age 101.

UT Southwestern researchers have found that a protein in the body’s innate immune system that responds to gut microbes can suppress the most common type of liver cancer.

UT Southwestern researchers report the first structural confirmation that endogenous – or self-made – molecules can set off innate immunity in mammals via a pair of immune cell proteins called the TLR4-MD-2 receptor complex.

Dallas is well-known for its oil industry, corporate headquarters, and technology startups. But did you know that the science behind some of the best-selling prescription drugs of all time was developed here?

Drs. Don Gammon and Nick Grishin have sequenced the genomes of the European gypsy moth and its even more destructive cousin, the Asian gypsy moth.

Metabolic differences could explain why some metastatic breast cancer cells rapidly generate tumors after migrating from primary tumors to the brain, while others linger for months or years before forming these secondary tumors, UT Southwestern scientists report in a new study.