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A genome engineering technique developed at UT Southwestern Medical Center helped make the institution a research partner in a new $185 million National Institutes of Health (NIH) initiative to build on findings of the Human Genome Project.

UT Southwestern scientists successfully employed a new type of gene therapy to treat mice with Duchenne muscular dystrophy (DMD)

Jere Mitchell, M.D., former director of the Harry S. Moss Heart Center at UT Southwestern Medical Center and an internationally recognized exercise physiologist whose seminal findings on maximal oxygen uptake changed conventional medical practice on bed rest and laid the foundation for central

Researchers at UT Southwestern announced successful results of a clinical trial for a commonly prescribed weight-loss drug called liraglutide.

Using a virus to purposely mutate genes that produce cancer-driving proteins could shed light on the resistance that inevitably develops to cancer drugs that target them, a new study led by UT Southwestern scientists suggests.

Jian Zhou, Ph.D., Assistant Professor in UT Southwestern’s Lyda Hill Department of Bioinformatics, has been awarded $1.5 million from the National Institutes of Health (NIH) to use artificial intelligence to investigate the three-dimensional structure of DNA and its impact on health.

A two-arm molecule can effectively deplete cancer-protecting cells inside tumors, allowing the immune system to fight off tumors without becoming overactive.

Katie Sturm had nearly gotten over the shock of learning she was pregnant with quadruplets when in February she suffered a seizure at work. She was diagnosed with a brain tumor, which was removed at UT Southwestern in March.

Endocannabinoids, signaling molecules produced in the body that share features with chemicals found in marijuana, can shut down genes needed for some pathogenic intestinal bacteria to colonize, multiply, and cause disease, new research led by UT Southwestern scientists shows.

UT Southwestern Medical Center’s Center for Depression Research and Clinical Care is collaborating with mental health colleagues across the country to expand detection and treatment for depression and other disorders across Texas as part of the Lone Star Depression Challenge.