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Scientists at UT Southwestern have discovered a key protein that helps the bacteria that causes Legionnaires’ disease to set up house in the cells of humans and other hosts.

Immunologists and geneticists at UT Southwestern Medical Center have discovered how vitamin A enters immune cells in the intestines – findings that could offer insight to treat digestive diseases and perhaps help improve the efficacy of some vaccines.

UT Southwestern is ranked among the top 20 medical schools for primary care and the top 25 for research in the United States, according to U.S. News & World Report’s 2023 Best Graduate Schools rankings.

Failure of human pluripotent stem cells (PSCs) to survive when grown with the PSCs of distantly related species occurs because of an innate immune reaction in the nonhuman cells, a study led by UT Southwestern Medical Center researchers suggests.

Researchers at UT Southwestern have uncovered evidence that the higher prevalence of “malignant” enlargement of the heart among blacks contributes to the higher incidence of heart failure in this population.

Drugs currently used to treat less than 10 percent of breast cancer patients could have broader effectiveness in treating ovarian and prostate cancers.

Aggressive methods for reducing high blood sugar following a severe stroke are not more effective than standard, lower risk treatments, according to a new study that offers clarity to a long-debated issue in stroke care.

The study reported “no significant difference in the effectiveness” of medical masks vs. N95 respirators for prevention of influenza or other viral respiratory illness.

UT Southwestern researchers report that lowering levels of the hormone leptin can reduce obesity, overeating, and the insulin resistance tied to diabetes – and they have found an antibody that can do that.

Artificial intelligence can help cancer patients start their radiation therapy sooner – and thereby decrease the odds of the cancer spreading – by instantly translating complex clinical data into an optimal plan of attack.