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UT Southwestern immunologists have uncovered a key pathogenic event prompted by obesity that can trigger severe forms of nonalcoholic fatty liver disease and potential liver failure.

A gene previously linked to autism spectrum disorder (ASD) by UT Southwestern Medical Center researchers appears to play an important role in steering cells in the brain’s hippocampus toward their ultimate identities, the same team reported in a new study. The findings, published in Science Advances

Antibodies that target specific tuberculosis (TB) proteins are effective at inhibiting the bacteria that cause TB, the infectious disease that claims the most lives worldwide, a study led by UT Southwestern Medical Center researchers found.

UT Southwestern Medical Center is leading three multicenter clinical trials funded by the National Institute on Drug Abuse (NIDA) focused on potential treatments for methamphetamine or cocaine addiction.

Oncology programs have sought to decrease visits by cancer patients to a hospital emergency department (ED) by offering resources such as 24/7 phone triage lines and urgent care clinics. However, these tend to be underutilized.

Overweight and obesity patients without diabetes who switched GLP-1 receptor agonist (GLP-1RA) drugs were more likely to stick with their treatment longer than those who didn’t switch, according to a new study by UT Southwestern Medical Center researchers.

The COVID-19 pandemic not only disrupted children’s education, recreation, and social lives, it also increased the prevalence of obesity in the U.S. pediatric population by roughly 1 million youngsters, according to a study led by UT Southwestern Medical Center researchers.

The world’s top competitors in the 2026 Olympics, which continue through Feb. 22, may offer a valuable lesson to those seeking to improve their workouts or just to get more active. While these elite athletes are performing at a peak level on a global stage, it’s the work they put in behind the

– A widely used fracture risk calculator may help guide surgical decisions to treat patients with an endocrine disorder called primary hyperparathyroidism (PHPT) that causes progressive bone loss, according to a study led by UT Southwestern Medical Center researchers.

A gene-editing delivery system developed by UT Southwestern Medical Center researchers simultaneously targeted the liver and lungs of a preclinical model of a rare genetic disease known as alpha-1 antitrypsin deficiency (AATD), significantly improving symptoms for months after a single treatment, a