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Lowering iron in fat cells prevented weight gain in mice: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2021/lowering-iron-in-fat-cells.html

Lowering iron content in fat cells prevented mice fed a high-fat diet from gaining excess weight and developing associated health problems by limiting the amount of lipids absorbed by the intestines

Early onset of diabetes, hypertension can predict early glaucoma: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2022/august-early-onset-of-diabetes.html

The earlier individuals develop Type 2 diabetes or hypertension in life, the earlier they are likely to develop primary open-angle glaucoma (POAG), the leading cause of irreversible blindness worldwide, researchers from UT Southwestern reported in a recent study.

Young pregnant adolescents at increased risk of preeclampsia, C-section, UTSW study shows : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2023/february-young-pregnant-adolescents.html

Young adolescents face different challenges in pregnancy compared with their older teenage peers and adults that are sometimes exacerbated by high rates of obesity, a new study by UT Southwestern researchers suggests.

Gene-editing nanoparticles correct stem cell mutations in cystic fibrosis models : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/june-gene-editing-nanoparticles.html

Researchers at UT Southwestern Medical Center developed nanoparticles that successfully edited the disease-causing gene in the lungs of a mouse model of cystic fibrosis (CF), swapping a mutated form for a healthy one that persisted in stem cells. Their findings, reported in Science, could offer hope

Why do women have more trouble after knee injuries? UTSW model explains: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/feb-women-knee-injuries.html

A computer model of the cellular environment inside the knee developed by UT Southwestern Medical Center researchers sheds light on why women tend to have worse outcomes after knee injuries than men. Their findings, published in Scientific Reports, could facilitate research into new therapies for

Stimulating fat cells with GIP receptor has potential to treat obesity: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/jan-fat-cells-with-incretin.html

Obese mice whose fat cells were genetically altered to produce an increased amount of the glucose-dependent insulinotropic polypeptide receptor (GIPR) lost more than a third of their body weight through a mechanism that burns energy, UT Southwestern Medical Center researchers report in a new study.

Autoimmune skin condition linked to higher risk of heart disease: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/jan-autoimmune-skin-condition.html

Patients with cutaneous lupus erythematosus (CLE), an autoimmune disease that causes skin inflammation, have a higher risk for atherosclerotic cardiovascular disease (ASCVD), or hardening of the arteries, UT Southwestern Medical Center researchers found.

Out of Africa: UT Southwestern cardiologist gets to the heart of Zambia’s No. 1 health threat : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/oct-strasserking-global-health.html

On a Thursday morning in Dallas, Fiona Strasserking, M.D., chats with her UT Southwestern colleague while internal medicine residents from the University of Zambia log on to their Zoom call. Rafic Berbarie, M.D., Associate Professor in UTSW’s Division of Cardiology, is today’s guest lecturer and the

AI can jump-start radiation therapy for cancer patients

https://www.utsouthwestern.edu/newsroom/articles/year-2020/ai-radiation-therapy.html

Artificial intelligence can help cancer patients start their radiation therapy sooner – and thereby decrease the odds of the cancer spreading – by instantly translating complex clinical data into an optimal plan of attack.

Combo diabetes treatment amplifies effectiveness, improves medication adherence: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2020/combo-diabetes-treatment.html

A once-daily combination treatment for those with uncontrolled Type 2 diabetes amplifies the treatment’s effects – lowering both weight and the number of hypoglycemic events, and improving quality of life and glucose control ¬– and makes participants more likely to adhere to their medications.