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Common analgesic gas aids in opening of blood-brain barrier: Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2025/may-analgesic-gas-blood-brain-barrier.html
Nitrous oxide, a commonly used analgesic gas, improved temporary opening of the blood-brain barrier (BBB) and gene therapy delivery in mouse models using focused ultrasound (FUS), UT Southwestern Medical Center researchers report in a new study.
Presurgical radiation may curb pancreatic cancer recurrence: Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2025/july-presurgical-radiation-pancreatic-cancer.html
Adding targeted radiation to chemotherapy prior to surgery may offer better control of pancreatic tumors – potentially reducing the rate of recurrence after treatment, according to a new study from UT Southwestern Medical Center. Published in Clinical Cancer Research, the novel study offers evidence
Protein linked to immunotherapy resistance in kidney cancer: Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2025/may-to-immunotherapy-resistance-kidney-cancer.html
A protein identified by researchers at UT Southwestern Medical Center may drive resistance to immune checkpoint inhibitors, a widely used form of immunotherapy to treat cancer.
Immune protein STING key for repairing, generating lysosomes: Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2025/april-immune-protein-sting-key.html
– The STING protein, known for helping cells fight viral infections by generating inflammation, also appears to function as a quality control sensor for organelles that serve as cellular waste disposal systems, UT Southwestern Medical Center researchers found. Their study, published in Molecular
Differences in survival persist despite access to cancer clinical trials: Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2025/april-differences-cancer-clinical-trials.html
Black and Hispanic children with high-risk neuroblastoma experience worse survival outcomes than their white peers, even when treated in frontline clinical trials, according to a study led by a UT Southwestern Medical Center researcher.
Cryo-EM technology reveals how vitamin K works in the body : Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2025/feb-cryo-em-technology-vitamin-k.html
Using a powerful microscopy technique, a team led by researchers at UT Southwestern Medical Center has gained insights into how the body uses vitamin K, an essential nutrient that plays a pivotal role in blood clotting and other physiological functions.
UTSW researchers use focused ultrasound to identify stroke biomarkers : Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2025/march-ultrasound-identify-stroke-biomarkers.html
A molecule called glial fibrillary acidic protein (GFAP) rose significantly in the blood of patients who underwent high-intensity focused ultrasound (HIFU), a procedure that is used to treat tremors and causes damage similar to a small stroke, UT Southwestern Medical Center scientists discovered in
UTSW study identifies RNA molecule that regulates cellular aging : Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2024/july-rna-molecule-cellular-aging.html
A team led by UT Southwestern Medical Center researchers has discovered a new way that cells regulate senescence, an irreversible end to cell division. The findings, published in Cell, could one day lead to new interventions for a variety of conditions associated with aging, including
New target to thwart multidrug resistance in cancer treatment: Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2025/feb-thwart-multidrug-resistance-cancer-treatment.html
Multidrug resistance in cancer can be overcome by combining a drug that blocks a key enzyme with another anticancer drug, according to a study in preclinical models led by researchers at UT Southwestern Medical Center. The findings, published in Science Advances, could have implications for patients
Shorter, safer protocol effectively treats triple-negative breast cancer: Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2025/jan-triple-negative-breast-cancer.html
A far shorter, simpler, and less toxic treatment protocol for patients with triple-negative breast cancer produced outcomes similar to the current standard of care, a clinical trial co-led by a UT Southwestern Medical Center researcher shows.