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A team led by UT Southwestern researchers has identified a key gene necessary for cells to consume and destroy viruses. The findings, reported online today in Nature, could lead to ways to manipulate this process to improve the immune system’s ability to combat viral infections, such as those

Being younger doesn’t protect against the dangers of COVID-19 if you are overweight, according to a new study from UT Southwestern.

Kidney damage that seemingly heals appears to mutate the DNA in the mitochondria of kidney cells, making the organ less resilient to future stressors and reducing its function over time, a study led by UT Southwestern Medical Center researchers shows.

By using a genetic technique they developed that forces cells to rid themselves of mitochondria, UT Southwestern Medical Center researchers are gaining new insights into the function of these critical organelles.

A preclinical model developed at UT Southwestern Medical Center that recapitulates a rare infant-onset form of diabetes suggests the condition stems from gradual damage to the pancreas through misregulation of a molecular pathway called the unfolded protein response (UPR).

A team led by UT Southwestern Medical Center researchers has uncovered the atomic structure of a protein complex pivotal to the function of motile cilia, the hair-like structures extending from the surfaces of many cell types that generate their movement.

Much like human beings, songbirds learn how to vocalize from their parents. Males imitate songs from their fathers and then sing to attract mates. Although the circuits that generate human speech are more complicated to decipher, the brains of songbirds offer a viable model for better understanding

A gene-editing delivery system developed by UT Southwestern Medical Center researchers simultaneously targeted the liver and lungs of a preclinical model of a rare genetic disease known as alpha-1 antitrypsin deficiency (AATD), significantly improving symptoms for months after a single treatment, a

UT Southwestern Medical Center researchers have discovered an RNA pathway that appears to push stem cells to form nephrons, the functional units of kidneys. Their findings, published in Nature Communications, could lead to therapies that increase the number of nephrons in individuals at risk of

More than two-thirds of 16-year-olds today have been through a traumatic event, such as the Central Texas flooding in July that killed over 130 people, including numerous children at summer camp.