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A far shorter, simpler, and less toxic treatment protocol for patients with triple-negative breast cancer produced outcomes similar to the current standard of care, a clinical trial co-led by a UT Southwestern Medical Center researcher shows.

A team led by UT Southwestern scientists has discovered a mechanism that promotes metastasis in pancreatic, breast, and potentially other cancers along with a new druggable therapeutic target based on this mechanism to block metastases.

A person’s IQ during high school is predictive of alcohol consumption later in life, according to a study by UT Southwestern Medical Center researchers published in Alcohol and Alcoholism.

Eight scientists and physicians in the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern have been awarded more than $11.5 million in grants from the Cancer Prevention and Research Institute of Texas (CPRIT) to support the state’s fight against cancer.

Bleeding is the most common cause of preventable death after injury. Researchers at Children’s Medical Center Dallas are seeking community consultation for possible future participation from parents and legal guardians in a study that will compare two resuscitation treatments (whole blood versus

A novel combination therapy slowed cognitive decline in elderly patients with a history of depression – a major risk factor for developing Alzheimer’s and other forms of dementia, a study led by UT Southwestern Medical Center’s new Chair and Professor of Psychiatry found.

Fat cells genetically altered to overproduce a hormone called FGF21 resulted in improved metabolic health and an extended lifespan in mice that were fed a high-fat diet, UT Southwestern Medical Center researchers report. The findings, published in Cell Metabolism, could lead to new interventions

UT Southwestern Medical Center scientists have identified a gene that appears to act as a master control switch for reactive gliosis, a prominent feature of many neurodegenerative diseases that is thought to contribute to their pathology.

Survival rates for out-of-hospital cardiac arrest (OHCA) fell during the early years of the COVID-19 pandemic, with Black and Hispanic patients experiencing larger decreases in survival, according to a study by UT Southwestern Medical Center researchers published in Resuscitation.

Female sex hormones can significantly enhance the progression of the rare neurodegenerative eye disease retinitis pigmentosa (RP), according to a preclinical study by researchers at UT Southwestern Medical Center. The findings, published in Science Advances, may lead to therapeutics to slow