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All weight loss isn't equal for reducing heart failure risk : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2020/all-weight-loss-isnt-equal-for-reducing-heart-failure-risk.html

Reducing the level of body fat and waist size are linked to a lower risk of heart failure in patients with type 2 diabetes, a study led by UT Southwestern researchers indicates.

Children’s Research Institute at UT Southwestern scientists identify feature of aggressive non-small cell lung cancer: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/feb-cri-utsw-aggressive-non-small-cell-lung-cancer.html

In localized non-small cell lung cancer (NSCLC), a tumor’s ability to use carbon from glucose to feed the tricarboxylic acid (TCA) cycle predicts cancer spread beyond the lung, months to years before metastases are clinically apparent. According to this new research from Children’s Medical Center

Repurposed drug has promising efficacy in non-small cell lung cancer: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/dec-efficacy-non-small-cell-lung-cancer.html

An FDA-approved drug used to treat multiple myeloma and lymphoma also shrank tumors in non-small cell lung cancer (NSCLC) with KRAS mutations, a clinical trial led by UT Southwestern Harold C. Simmons Comprehensive Cancer Center researchers showed.

End-of-life care more aggressive for cancer patients with defibrillators: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/jan-end-of-life-care-more-aggressive-cancer-patients.html

Patients with advanced cancer who also had cardiac defibrillators were more likely than those without these implants to receive aggressive end-of-life care, a team led by UT Southwestern Medical Center researchers found in a new study.

Two UT Southwestern scientists selected as HHMI Hanna Gray Fellows : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2022/september-hanna-h-gray-fellows-program.html

Two UT Southwestern postdoctoral fellows – Gabriel Muhire Gihani, Ph.D., and Victor Lopez, Ph.D. – are among 25 early career scientists in the United States selected as 2022 Hanna H. Gray Fellows.

Key protein behind necroptotic cell death could drive new treatment strategies: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/dec-key-protein-necroptotic-cell-death.html

Researchers at UT Southwestern Medical Center have identified a protein that causes human cell membranes to break open in a form of inflammatory programmed cell death called necroptosis.

Differences in survival persist despite access to cancer clinical trials: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/april-differences-cancer-clinical-trials.html

Black and Hispanic children with high-risk neuroblastoma experience worse survival outcomes than their white peers, even when treated in frontline clinical trials, according to a study led by a UT Southwestern Medical Center researcher.

Immune protein STING key for repairing, generating lysosomes: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/april-immune-protein-sting-key.html

– The STING protein, known for helping cells fight viral infections by generating inflammation, also appears to function as a quality control sensor for organelles that serve as cellular waste disposal systems, UT Southwestern Medical Center researchers found. Their study, published in Molecular

Lifelong physical activity may slow cognitive decline: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/april-physical-activity-cognitive-decline.html

High levels of physical activity may mitigate brain loss in adults and help maintain long-term cognitive health, researchers at UT Southwestern Medical Center report in a study published in the Journal of Applied Physiology.

UTSW researchers use focused ultrasound to identify stroke biomarkers : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/march-ultrasound-identify-stroke-biomarkers.html

A molecule called glial fibrillary acidic protein (GFAP) rose significantly in the blood of patients who underwent high-intensity focused ultrasound (HIFU), a procedure that is used to treat tremors and causes damage similar to a small stroke, UT Southwestern Medical Center scientists discovered in