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More than a dozen UT Southwestern Medical Center scientists are included on the 2023 Highly Cited Researchers list, which recognizes the top 1% of researchers from around the world who have demonstrated significant and broad influence in their chosen field or fields of research.

By completely or even partially depleting a protein called midnolin in B cells, UT Southwestern Medical Center researchers suppressed leukemia and lymphoma in a mouse model genetically prone to these cancers.

Patients with moderate to severe treatment-resistant depression (TRD) might have better symptom relief from ketamine infusions than from electroconvulsive therapy (ECT), but those with severe TRD could benefit more from ECT early in treatment, an analysis led by a UT Southwestern Medical Center

Total knee replacements performed with the help of a surgical robot have better outcomes on average than similar surgeries performed manually but can cost significantly more, a new study by UT Southwestern Medical Center researchers shows.

Caring for someone with dementia or Alzheimer’s disease is challenging. In addition to the financial and physical demands, many caregivers are unprepared for the stress of trying to effectively communicate with a loved one who may be prone to agitation, verbal aggression, and hallucinations.

Newly developed artificial intelligence (AI) programs accurately predicted the role of DNA’s regulatory elements and three-dimensional (3D) structure based solely on its raw sequence, according to two recent studies in Nature Genetics.

For the third year in a row, UT Southwestern is ranked as the top health care institution globally by Nature Index for publishing high-quality research in all subjects and in the life sciences.

UT Southwestern is joining with medical centers around the nation to apply advanced sequencing to pediatric brain tumors as part of the National Cancer Institute’s new Molecular Characterization Initiative, a subset of the Cancer Moonshot Childhood Cancer Initiative.

A multidisciplinary effort to improve care for older patients who arrive at the emergency room with a hip fracture has decreased the time before they have surgery, shortened hospital stays, and resulted in better follow-up care, UT Southwestern physicians reported in Geriatric Nursing.

A gene that’s well known for its role in turning on tumor-suppressing genes when cells become stressed also keeps potential tumor-driving genes turned off, UT Southwestern researchers report in a new study.