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Kidney damage that seemingly heals appears to mutate the DNA in the mitochondria of kidney cells, making the organ less resilient to future stressors and reducing its function over time, a study led by UT Southwestern Medical Center researchers shows.

A new tool called PHOTON, developed by scientists at UT Southwestern Medical Center, can identify RNA molecules at their native locations within cells – providing valuable clues to where different RNA species are distributed spatially in response to various cellular cues.

A singer’s primary genre can impact the likelihood of developing vocal fold injury and may even influence the specific type of injury that occurs, a recent study by UT Southwestern researchers suggests.

Tripling the standard dose of semaglutide, a popular drug prescribed to treat obesity, led to significantly greater weight loss and associated metabolic benefits without increased risk of serious side effects, a multicenter clinical trial led by a UT Southwestern Medical Center researcher shows.

Zhijian “James” Chen, Ph.D., Professor in the Department of Molecular Biology at UT Southwestern Medical Center and one of the world’s top researchers on innate immunity, has been awarded the 2026 Elaine Redding Brinster Prize in Science or Medicine.

Researchers at UT Southwestern Medical Center have identified a novel parameter of T cells that could help oncologists anticipate which patients would be most likely to develop immunotherapy toxicity.

A mutation in the gene that causes cystic fibrosis may accelerate heart function decline in those with Duchenne muscular dystrophy (DMD), a new study by UT Southwestern researchers suggests.

Complications after an amputation left Scott Bryson, a 50-year-old father of three, unable to walk. But in June 2023, he took his first steps in nearly a decade after receiving a revolutionary surgical procedure at UT Southwestern Medical Center.

Members of UT Southwestern Medical School’s Class of 2025 gathered with anticipation inside the Bryan Williams, M.D., Student Center gymnasium Friday morning to learn where they will begin the next phase of their training as residents.

You’re eating or drinking something frozen, like a snow cone, ice cream, or ice pops – probably a bit too eagerly – and you get one of those sudden-onset, painful headaches known as “brain freeze.” Man, does it hurt, but usually not for long, and it’s not harmful, according to an expert at UT