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Team discovers broken ‘brake' of cancer mutation machine: Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2023/aug-mutation-machine-for-cancers.html
Loss of a gene known as SYNCRIP in prostate cancer tumors unleashes cellular machinery that creates random mutations throughout the genome that drive resistance to targeted treatments, a team led by UT Southwestern Medical Center researchers discovered.
Protein inhibits development of COVID-19 in live animals: Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2023/july-covid-19-in-live-animals.html
A mammalian protein previously shown by UT Southwestern microbiologists to inhibit the virus that causes COVID-19 in cell culture also protected live mouse models, significantly limiting infection in the lung cells and diminishing the symptoms.
UT Southwestern ranked top health care institution globally for published research by Nature Index: Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2022/october-top-healthcare-institution.html
For the third year in a row, UT Southwestern is ranked as the top health care institution globally by Nature Index for publishing high-quality research in all subjects and in the life sciences.
Artificial intelligence algorithm developed to assess metastatic potential in skin cancers: Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2021/ai-melanoma.html
Using artificial intelligence (AI), researchers from UT Southwestern have developed a way to accurately predict which skin cancers are highly metastatic.
UTSW researchers identify key player in cellular response to stress: Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2022/september-cellular-response-to-stress.html
An enzyme called Fic, whose biochemical role was discovered at UT Southwestern more than a dozen years ago, appears to play a crucial part in guiding the cellular response to stress, a new study suggests.
Some genetic sequencing fail to analyze large segments of DNA: Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2020/genetic-sequencing.html
Children who undergo expansive genetic sequencing may not be getting the thorough DNA analysis their parents were expecting, say experts at UT Southwestern Medical Center.
UT Southwestern researchers identify a gene therapy target for polycystic kidney disease – UT Southwestern Medical Center psychiatric hospital: Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2022/september-polycystic-kidney-disease.html
Blocking the inhibition of PKD1 and PKD2 gene expression by deleting a binding site for microRNAs hindered the formation and growth of kidney cysts in autosomal dominant polycystic kidney disease (ADPKD) models, UT Southwestern researchers reported.
Study finds risk factors for severe COVID-19 cases in children : Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2023/nov-severe-covid19-cases.html
Children who had preexisting health problems or who lived in the Southern United States had a higher risk for severe health outcomes from acute COVID-19 infections, according to researchers at UT Southwestern Medical Center.
Long-haul COVID deserves more attention, UTSW expert says: Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2022/august-long-haul-covid.html
While public attention has been focused on the million-plus Americans who have died from COVID-19 and the ongoing level of cases and hospitalizations, tens of millions of patients have developed life-altering symptoms that linger long after their COVID-19 infection clears.
Researchers use machine learning to identify autism blood biomarkers: Newsroom - UT Southwestern, Dallas, Texas
https://www.utsouthwestern.edu/newsroom/articles/year-2021/autism-blood-biomarkers.html
Using machine learning tools to analyze hundreds of proteins, UT Southwestern researchers have identified a group of biomarkers in blood that could lead to an earlier diagnosis of children with autism spectrum disorder (ASD) and, in turn, more effective therapies sooner.