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Combining a common chemotherapy drug with an experimental nanotechnology allowed the drug to cross the blood-brain barrier and increased the survival rate in a mouse model of glioblastoma up to 50%, a team led by researchers from UT Southwestern Medical Center and UT Dallas found.

Simple changes in patient ventilation procedures during out-of-hospital cardiopulmonary resuscitation (CPR) could lead to a dramatic improvement in cardiac arrest survival rates.

By completely or even partially depleting a protein called midnolin in B cells, UT Southwestern Medical Center researchers suppressed leukemia and lymphoma in a mouse model genetically prone to these cancers.

A molecule has demonstrated its ability to kill tumor cells and incite an immune response in preclinical models of small cell lung cancer (SCLC), according to UT Southwestern Medical Center researchers.

Total knee replacements performed with the help of a surgical robot have better outcomes on average than similar surgeries performed manually but can cost significantly more, a new study by UT Southwestern Medical Center researchers shows.

A gene called Npas4, already known to play a key role in balancing excitatory and inhibitory inputs in brain cells, appears to also be a master timekeeper for the brain’s circadian clock, new research led by UT Southwestern scientists suggests.

Whether it’s after a natural disaster, a fatal shooting, or a tragedy closer to home, parents may find themselves trying to navigate difficult conversations with their children. What to say is just as important as what not to say, according to experts at UT Southwestern Medical Center. Children are

Automated external defibrillators (AEDs) are underutilized during cardiac arrest episodes despite laws in some states requiring their availability in high-risk areas such as athletic facilities, researchers at UT Southwestern Medical Center found. The devices can save lives by shocking the heart

– Newborn boys are significantly more likely than girls to have a brain injury called hypoxic-ischemic encephalopathy (HIE), researchers at UT Southwestern Medical Center and Children’s Health Dallas report.

Forty percent of critically ill children whose parents or other caregivers declined tracheostomies died within 24 months, and half of all deaths occurred within six weeks, researchers at UT Southwestern Medical Center and Children’s Medical Center Dallas found.