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Hunting down the mutations that cause cancer drug resistance: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2021/cancer-drug-resistance.html

Using a virus to purposely mutate genes that produce cancer-driving proteins could shed light on the resistance that inevitably develops to cancer drugs that target them, a new study led by UT Southwestern scientists suggests.

UT Southwestern investigators report first analysis of pioneering kidney cancer radiation approach in clinical trial: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2021/kidney-cancer-radiation.html

A new approach using precisely targeted, high-dose radiation to treat invasive kidney cancer proves safe, based on a clinical trial by the UT Southwestern Harold C. Simmons Comprehensive Cancer Center’s kidney cancer program.

In Memoriam: Dr. Jere Mitchell helped lay foundations of exercise physiology, changed medical practice on bed rest: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2021/in-memoriam-mitchell.html

Jere Mitchell, M.D., former director of the Harry S. Moss Heart Center at UT Southwestern Medical Center and an internationally recognized exercise physiologist whose seminal findings on maximal oxygen uptake changed conventional medical practice on bed rest and laid the foundation for central

Biomarkers linked to side effects from cancer immunotherapy

https://www.utsouthwestern.edu/newsroom/articles/year-2025/sept-immunotherapy-biomarkers.html

A team led by UT Southwestern Medical Center scientists has identified early signals from the immune system that could help predict which cancer patients are most likely to develop harmful side effects from immunotherapy.

STINGing tumors with nanoparticles: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2021/stinging-tumors-with-nanoparticles.html

A new nanoparticle-based drug can boost the body’s innate immune system and make it more effective at fighting off tumors, researchers at UT Southwestern have shown.

Austin tennis coach wins gold medal after lung transplant: Newsroom - UT Southwestern, Dallas, TX

https://www.utsouthwestern.edu/newsroom/articles/year-2019/lung-transplant.html

Competing in the World Transplant Games in Newcastle, England, as part of Team USA, Genie Kilpatrick won a gold medal in women’s tennis.

Geneticists ID molecular pathway for autism-related disorder: Newsroom, UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2019/molecular-pathway-kos.html

 Discovery of molecular trigger for autism-related disorder leads scientists to test potential therapy on mice.

A MEG powerhouse: How UTSW is pushing the limits of brain research, care: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/aug-meg-powerhouse.html

Most days, neurologist Sasha Alick-Lindstrom, M.D., M.P.H., FAAN, FACNS, FAES, can be found staring at rows of brain signals on multiple computer screens, inspecting the squiggly lines for any irregularities or spikes of electrical activity.

Kidney cancer drug shows promise against dangerous calcium imbalance caused by tumors: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/oct-kidney-cancer-drug.html

Elevated calcium levels in the blood – a complication of kidney cancers known as hypercalcemia – may be successfully treated with a class of medications called HIF-2 inhibitors developed by UT Southwestern Medical Center, a new study shows. The findings, published in Cancer Discovery by a team at

UTSW discovery opens door to novel strategies for hard-to-treat cancers : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/oct-hard-to-treat-cancers.html

UT Southwestern Medical Center researchers have identified two distinct populations of cells known as antigen-presenting cancer-associated fibroblasts (apCAFs) that appear to support the survival and growth of malignant tumors. Their findings, reported in Cancer Cell, could one day lead to new