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SORTing gene editing tools to where they're needed - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2020/sorting-gene-editing-tools.html

Scientists at UTSW have developed a technology that shuttles nanoparticles carrying gene editing and protein replacement tools to the specific tissues where they're needed.

Tumor mutation associated with drug-resistant liver cancer, UT Southwestern study finds: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2023/june-tumor-mutation-drug-resistant-liver-cancer.html

A genetic marker discovered by UT Southwestern Medical Center researchers could help physicians predict which patients with hepatocellular carcinoma are most likely to develop resistance to the drug lenvatinib. The finding, published in the journal Gastroenterology, may lead to alternative

New tool sheds light on where RNA is found in cells : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/june-tool-sheds-light-on-rna.html

A new tool called PHOTON, developed by scientists at UT Southwestern Medical Center, can identify RNA molecules at their native locations within cells – providing valuable clues to where different RNA species are distributed spatially in response to various cellular cues.

COVID-19 pandemic linked to increases in childhood obesity: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/dec-covid-19-pandemic-childhood-obesity.html

The COVID-19 pandemic not only disrupted children’s education, recreation, and social lives, it also increased the prevalence of obesity in the U.S. pediatric population by roughly 1 million youngsters, according to a study led by UT Southwestern Medical Center researchers.

Children’s Research Institute at UT Southwestern scientists identify feature of aggressive non-small cell lung cancer: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/feb-cri-utsw-aggressive-non-small-cell-lung-cancer.html

In localized non-small cell lung cancer (NSCLC), a tumor’s ability to use carbon from glucose to feed the tricarboxylic acid (TCA) cycle predicts cancer spread beyond the lung, months to years before metastases are clinically apparent. According to this new research from Children’s Medical Center

End-of-life care more aggressive for cancer patients with defibrillators: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/jan-end-of-life-care-more-aggressive-cancer-patients.html

Patients with advanced cancer who also had cardiac defibrillators were more likely than those without these implants to receive aggressive end-of-life care, a team led by UT Southwestern Medical Center researchers found in a new study.

Repurposed drug has promising efficacy in non-small cell lung cancer: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/dec-efficacy-non-small-cell-lung-cancer.html

An FDA-approved drug used to treat multiple myeloma and lymphoma also shrank tumors in non-small cell lung cancer (NSCLC) with KRAS mutations, a clinical trial led by UT Southwestern Harold C. Simmons Comprehensive Cancer Center researchers showed.

UTSW study finds potential strategy for fighting obesity: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2021/utsw-study-finds-potential-strategy-for-fighting-obesity.html

UT Southwestern scientists may have identified a method of safely mimicking the weight-loss benefits of a plant compound that – despite its harmful side effects – hold critical answers to developing therapies for obesity.

UT Southwestern surgeon offers insight on elbow injuries among young baseball players: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2023/april-elbow-injuries-among-young-baseball-players.html

Tears or ruptures of the ulnar collateral ligament (UCL) are the most common elbow injury among baseball players from youth leagues to the major leagues, especially pitchers.

Missing protein helps small cell lung cancer evade immune defenses: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2021/missing-protein-helps-small-cell-lung-cancer.html

Small cell lung cancer (SCLC) cells are missing a surface protein that triggers an immune response, allowing them to hide from one of the body’s key cancer defenses, a new study led by UT Southwestern researchers suggests.