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Researchers have discovered that a molecule – estrogen-related receptor gamma, or ESRRG – becomes hyperactive and promotes tumor cell survival in retinoblastoma.

Scientists at UT Southwestern have discovered a molecular switch to restore the regenerative ability of adult heart cells.

A multicenter study performed by a large international consortium that includes UT Southwestern has outlined a set of risk factors and outcomes for patients with autoimmune hepatitis (AIH) that recurs after liver transplantation.

Researchers at UT Southwestern’s Harold C. Simmons Comprehensive Cancer Center are developing an innovative interface to make the wealth of genomics data from next-generation sequencing visible and actionable in real time for clinicians and researchers.

A normal process called cell competition, in which healthy tissues eliminate unhealthy cells, could be responsible for cancer relapses in patients months or years after they were declared cancer-free, a new study by UT Southwestern researchers suggests.

A UT Southwestern study suggests why urinary tract infections have such a high recurrence rate in postmenopausal women.

New research from UT Southwestern suggests that RNA exosomes– the cellular machines that degrade old molecules of RNA – play a key role in the development of B cells, which are critical to the immune system’s ability to protect against infection.

Individuals should weigh their own personal health and risk levels in deciding when to receive a second booster of the COVID-19 vaccine, UT Southwestern infectious diseases experts advise.

Changes in habits during the pandemic can lead to unexpected health issues with feet and ankles. Orthopedic surgeon Kshitij Manchanda, M.D. at UT Southwestern Orthopaedic Surgery and Sports Medicine has seen an increase in both reported injuries and chronic problems.

Editing a gene that prompts a cascade of damage after a heart attack appeared to reverse this inevitable course in mice, leaving their hearts remarkably unharmed, a new study by UT Southwestern scientists showed.