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Using gene editing in a preclinical model, researchers at UT Southwestern Medical Center blocked the symptoms of a rare smooth muscle disease before they developed. Their findings, published in Circulation, could eventually lead to gene therapies for this and other genetic diseases affecting smooth

When cancer cells metastasize, breaking away from the primary tumor and spreading to blood, tissue, or lymph nodes, the disease is at its most lethal.

Repeated sessions of electrical stimulation to brain networks associated with memory improved verbal learning in some Alzheimer’s disease patients for up to eight weeks in a preliminary trial led by UT Southwestern Medical Center researchers. The findings, published in The Journal of Prevention of

UT Southwestern physicians have developed an improved targeting method, four-tract tractography, to personalize MRI-guided, high-intensity focused ultrasound.

Obese mice whose fat cells were genetically altered to produce an increased amount of the glucose-dependent insulinotropic polypeptide receptor (GIPR) lost more than a third of their body weight through a mechanism that burns energy, UT Southwestern Medical Center researchers report in a new study.

Internationally recognized epidemiologist Saad B. Omer, M.B.B.S, Ph.D., who currently directs the Yale Institute for Global Health, has been appointed the inaugural Dean of the Peter O’Donnell Jr. School of Public Health at UT Southwestern Medical Center.

Italian medical geneticist Andrea Ballabio, M.D., an internationally recognized scientist who has devoted his career to elucidating the mechanisms underlying genetic diseases, has been named the recipient of the 2025 Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern Medical Center.

UT Southwestern Medical Center researchers have identified two distinct populations of cells known as antigen-presenting cancer-associated fibroblasts (apCAFs) that appear to support the survival and growth of malignant tumors. Their findings, reported in Cancer Cell, could one day lead to new

Automated external defibrillators (AEDs) are underutilized during cardiac arrest episodes despite laws in some states requiring their availability in high-risk areas such as athletic facilities, researchers at UT Southwestern Medical Center found. The devices can save lives by shocking the heart

A nanoparticle-based therapy developed by UT Southwestern Medical Center scientists stimulated an immune pathway that eradicated tumors in mouse models of various cancer types.