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Gene-editing system targets multiple organs simultaneously: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/june-gene-editing-system.html

A gene-editing delivery system developed by UT Southwestern Medical Center researchers simultaneously targeted the liver and lungs of a preclinical model of a rare genetic disease known as alpha-1 antitrypsin deficiency (AATD), significantly improving symptoms for months after a single treatment, a

Giving cells an appetite for viruses: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2020/giving-cells-an-appetite-for-viruses.html

A team led by UT Southwestern researchers has identified a key gene necessary for cells to consume and destroy viruses. The findings, reported online today in Nature, could lead to ways to manipulate this process to improve the immune system’s ability to combat viral infections, such as those

New options at Dallas food pantry boost food security: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/feb-dallas-food-pantry.html

Nutritious meal kits and no-prep meals improved food security and perceived dietary quality among clients of a Dallas food pantry, according to a pilot study led by UT Southwestern Medical Center.

AI chatbots are mostly correct, but incomplete, on endometriosis: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/feb-ai-chatbots-endometriosis.html

Three of the leading chatbots can provide basic information about endometriosis, a painful gynecologic condition that affects as many as 1 in 10 women, but their responses are not as comprehensive as the guidance from health care providers, according to a study by UT Southwestern Medical Center

Researchers create ‘wiring diagram’ for key songbird brain region: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/april-wiring-diagram-songbird.html

Much like human beings, songbirds learn how to vocalize from their parents. Males imitate songs from their fathers and then sing to attract mates. Although the circuits that generate human speech are more complicated to decipher, the brains of songbirds offer a viable model for better understanding

Neonatal diabetes model provides insights on how condition develops: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/april-neonatal-diabetes-model.html

A preclinical model developed at UT Southwestern Medical Center that recapitulates a rare infant-onset form of diabetes suggests the condition stems from gradual damage to the pancreas through misregulation of a molecular pathway called the unfolded protein response (UPR).

Study sheds light on cilia’s function in cells, role in diseases : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/july-light-on-cilias-function.html

A team led by UT Southwestern Medical Center researchers has uncovered the atomic structure of a protein complex pivotal to the function of motile cilia, the hair-like structures extending from the surfaces of many cell types that generate their movement.

Molecular imaging innovator Samuel Achilefu, Ph.D., to launch, lead Biomedical Engineering Department at UT Southwestern: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2022/achilefu-molecular-imaging-innovator.html

Samuel Achilefu, Ph.D., nationally recognized for expertise in molecular imaging and its application in treating human diseases, has been selected inaugural Chair to launch a new Department of Biomedical Engineering (BME) at UT Southwestern Medical Center.

Researchers uncover a potential treatment for an aggressive form of lung cancer: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2021/aggressive-form-of-lung-cancer.html

Researchers at the Children’s Medical Center Research Institute at UT Southwestern (CRI) have discovered a new metabolic vulnerability in a highly aggressive form of non-small cell lung cancer (NSCLC).

RNA molecular pathway steers stem cells to aid kidney development: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/june-rna-molecular-pathway.html

UT Southwestern Medical Center researchers have discovered an RNA pathway that appears to push stem cells to form nephrons, the functional units of kidneys. Their findings, published in Nature Communications, could lead to therapies that increase the number of nephrons in individuals at risk of