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UT Southwestern faculty have discovered what appears to be an Achilles’ heel in ovarian cancers, as well as new biomarkers that could point to which patients are the best candidates for possible new treatments.

Researchers and data scientists at UT Southwestern Medical Center and MD Anderson Cancer Center have developed an artificial intelligence technique that can identify which cell surface peptides produced by cancer cells called neoantigens are recognized by the immune system.

New research has uncovered a surprising role for so-called “jumping” genes that have traditionally been considered a source of genetic mutations responsible for a number of human diseases.

With knee replacement surgery becoming more common, Varatharaj Mounasamy, M.D., Professor of Orthopaedic Surgery at UT Southwestern Medical Center who specializes in hip and knee replacements, recommends taking off from work for a few weeks, joining a class to learn more about joint replacement, and

UT Southwestern Medical Center has informed affected patients of an inappropriate disclosure of their names and email addresses through the use of a third-party vendor. The vendor was used to send invitations to an event for the Kidney Cancer Program.

Pregnant women, who are at increased risk of preterm birth or pregnancy loss if they develop a severe case of COVID-19, need the best possible guidance on whether they should receive a COVID-19 vaccine.

The dominant form of heart failure worldwide appears to be caused by a strong, bidirectional interaction between the body’s response to metabolic stress and the immune system, according to a review article written by UT Southwestern researchers and colleagues.

UT Southwestern Medical Center scientists have identified the first two cases of the B.1.617.2 (Indian origin) variant of COVID-19 infection in North Texas using next-generation sequencing technologies along with targeted PCR testing.

Funded by a Specialized Program of Research Excellence (SPORE) award from the National Cancer Institute (NCI), the Kidney Cancer Program (KCP) at UT Southwestern’s Harold C. Simmons Comprehensive Cancer Center reports the largest and most diverse catalog of kidney cancer tumor models to date.

A drug in clinical trials as a treatment for metabolic dysfunction-associated steatotic liver disease (MASLD) works with a one-two punch that shuts down triglyceride production and fatty acid synthesis in liver cells, UT Southwestern Medical Center researchers show in a new study.