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In Memoriam: David J. Mangelsdorf, Ph.D., pioneer in orphan nuclear receptor research and Chair of Pharmacology Published on: August 09, 2025 • By: Newsroom Share Share on Facebook Share on Twitter Share on LinkedIn Email this page Print this page DALLAS – Aug. 9, 2025 – David J. Mangelsdorf, Ph.D., Chair and Professor of Pharmacology at UT Southwestern Medical Center, a visionary scientist who pioneered the once-obscure realm of orphan nuclear receptors (a class of proteins involved in gene

A microprotein called adipogenin appears to play a key role in helping fat cells store lipid droplets – a phenomenon that’s pivotal for metabolic health, a study co-led by UT Southwestern Medical Center researchers shows.

Artificial intelligence (AI) has become a go-to tool in health care, helping clinicians such as radiologists make diagnoses and personalize care. But what do patients think about this?

The traditional lipid panel may not give the full picture of cholesterol-related heart disease risk for many Americans, according to a study led by UT Southwestern Medical Center researchers and published in JAMA Cardiology.

Researchers have identified factors associated with survival for patients initially diagnosed with metastatic breast cancer who were seen at UT Southwestern Medical Center and its affiliated sites.

Members of UT Southwestern Medical School’s Class of 2025 gathered with anticipation inside the Bryan Williams, M.D., Student Center gymnasium Friday morning to learn where they will begin the next phase of their training as residents.

Obese mice whose fat cells were genetically altered to produce an increased amount of the glucose-dependent insulinotropic polypeptide receptor (GIPR) lost more than a third of their body weight through a mechanism that burns energy, UT Southwestern Medical Center researchers report in a new study.

This season of office parties and extravagant meals is filled with tempting treats that can make it difficult to reach your health goals.

An experimental treatment for depression that triggers seizures with magnets significantly improved mental health in patients without some cognitive effects associated with electroconvulsive therapy (ECT), a clinical trial led by UT Southwestern Medical Center researchers showed.

Yunsun Nam, Ph.D., Professor of Biochemistry and Biophysics at UT Southwestern Medical Center, will receive the 2026 Edith and Peter O’Donnell Award in Biological Sciences from the Texas Academy of Medicine, Engineering, Science & Technology (TAMEST) for her research into how RNAs and proteins