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UT Southwestern scientists discover antiviral immune pathway: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/april-antiviral-immune-pathway.html

By focusing on a poxvirus protein, a team led by UT Southwestern Medical Center scientists has discovered an antiviral immune pathway that broadly fights a wide variety of viruses.

UTSW Research: Python guts, emergency room visits, and more: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/dec-clinical-research-roundup.html

Oncology programs have sought to decrease visits by cancer patients to a hospital emergency department (ED) by offering resources such as 24/7 phone triage lines and urgent care clinics. However, these tend to be underutilized.

Researchers create ‘wiring diagram’ for key songbird brain region: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/april-wiring-diagram-songbird.html

Much like human beings, songbirds learn how to vocalize from their parents. Males imitate songs from their fathers and then sing to attract mates. Although the circuits that generate human speech are more complicated to decipher, the brains of songbirds offer a viable model for better understanding

Neonatal diabetes model provides insights on how condition develops: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/april-neonatal-diabetes-model.html

A preclinical model developed at UT Southwestern Medical Center that recapitulates a rare infant-onset form of diabetes suggests the condition stems from gradual damage to the pancreas through misregulation of a molecular pathway called the unfolded protein response (UPR).

UT Southwestern selects physician leader Jonathan Efron, M.D., to oversee Health System - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2023/sept-efron-health-system.html

Colorectal surgeon who led Johns Hopkins physician practice to focus on integration of clinical, research, education missions at UTSW

Upper urinary tract cancer drug may offer long-term benefits: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/march-urinary-cancer-drug.html

While randomized comparative trials are needed, a relatively new treatment option for upper urinary tract cancers shows promise for lowering long-term recurrence in many patients with low-grade disease, according to a multicenter study led by researchers at UT Southwestern Medical Center.

Giving cells an appetite for viruses: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2020/giving-cells-an-appetite-for-viruses.html

A team led by UT Southwestern researchers has identified a key gene necessary for cells to consume and destroy viruses. The findings, reported online today in Nature, could lead to ways to manipulate this process to improve the immune system’s ability to combat viral infections, such as those

RNA molecular pathway steers stem cells to aid kidney development: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/june-rna-molecular-pathway.html

UT Southwestern Medical Center researchers have discovered an RNA pathway that appears to push stem cells to form nephrons, the functional units of kidneys. Their findings, published in Nature Communications, could lead to therapies that increase the number of nephrons in individuals at risk of

Study sheds light on cilia’s function in cells, role in diseases : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/july-light-on-cilias-function.html

A team led by UT Southwestern Medical Center researchers has uncovered the atomic structure of a protein complex pivotal to the function of motile cilia, the hair-like structures extending from the surfaces of many cell types that generate their movement.

Gene-editing system targets multiple organs simultaneously: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/june-gene-editing-system.html

A gene-editing delivery system developed by UT Southwestern Medical Center researchers simultaneously targeted the liver and lungs of a preclinical model of a rare genetic disease known as alpha-1 antitrypsin deficiency (AATD), significantly improving symptoms for months after a single treatment, a