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Bioengineered approach shows promise in ulcerative colitis: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/jan-bioengineered-approach-ulcerative-colitis.html

By taking advantage of mechanisms that allow cancer cells to evade immune attack, UT Southwestern Medical Center researchers have developed a new strategy that has potential for treating ulcerative colitis.

How gut bacteria become ‘persisters’ to avoid antibiotics: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/feb-gut-bacteria-become-persisters.html

A subpopulation of gut bacteria given a commonly used antibiotic became “persisters” that were able to survive without developing true resistance, UT Southwestern Medical Center scientists discovered.

Oral contraceptive use may reduce muscle-tendon injuries: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/april-oral-contraceptive-muscle-tendon-injuries.html

Women who take oral contraceptives may be significantly less likely to experience certain musculoskeletal injuries than women who do not take the drugs or men, according to a study by UT Southwestern Medical Center.

Gene therapy offers hope for giant axonal neuropathy patients: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/march-gene-therapy-axonal-neuropathy-patients.html

A gene therapy developed by researchers at UT Southwestern Medical Center for a rare disease called giant axonal neuropathy (GAN) was well tolerated in pediatric patients and showed clear benefits, a new study reports.

UT Southwestern researchers create model to assess post-tonsillectomy bleed rates: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2023/march-post-tonsillectomy-bleed-rates.html

Researchers led by a team at UT Southwestern Medical Center have created a statistical model to identify standards for typical, high, or low rates of bleeding after pediatric tonsillectomies.

Diabetes drug metformin may protect against radiation exposure: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/aug-diabetes-drug-metformin.html

Metformin, a well-tolerated diabetes drug prescribed to as many as 150 million people worldwide, may also protect cells from radioactive damage, UT Southwestern Medical Center researchers report.

UT Southwestern researchers discover mechanism responsible for genome rearrangements: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2023/may-mechanism-responsible-for-genome-rearrangements.html

The goal of every dividing cell is to accurately segregate its genome into two genetically identical daughter cells. However, this process often goes awry and may be responsible for a new class of chromosomal abnormalities found in cancers and congenital disorders, UT Southwestern Medical Center

Stimulating fat cells with GIP receptor has potential to treat obesity: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/jan-fat-cells-with-incretin.html

Obese mice whose fat cells were genetically altered to produce an increased amount of the glucose-dependent insulinotropic polypeptide receptor (GIPR) lost more than a third of their body weight through a mechanism that burns energy, UT Southwestern Medical Center researchers report in a new study.

Personal approach reduces opioids after cesarean deliveries: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2023/dec-opioids-prescribed-after-c-section.html

Tailoring prescriptions individually to a patient’s needs after cesarean delivery can decrease opioid use while successfully managing post-surgical pain, according to a new study by researchers at UT Southwestern Medical Center. The change in protocol, detailed in a study published in the American

Protein plays dual role in causing, preventing sepsis: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/march-protein-preventing-sepsis.html

A protein called angiopoietin-2 (ANGPT2) can both inhibit and encourage blood vessel changes critical for sepsis, a leading cause of hospital deaths worldwide, a new study led by UT Southwestern Medical Center researchers shows.