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A gene-editing delivery system developed by UT Southwestern Medical Center researchers simultaneously targeted the liver and lungs of a preclinical model of a rare genetic disease known as alpha-1 antitrypsin deficiency (AATD), significantly improving symptoms for months after a single treatment, a

A preclinical model developed at UT Southwestern Medical Center that recapitulates a rare infant-onset form of diabetes suggests the condition stems from gradual damage to the pancreas through misregulation of a molecular pathway called the unfolded protein response (UPR).

Much like human beings, songbirds learn how to vocalize from their parents. Males imitate songs from their fathers and then sing to attract mates. Although the circuits that generate human speech are more complicated to decipher, the brains of songbirds offer a viable model for better understanding

Lorena Saelices Gomez, Ph.D., Assistant Professor of Biophysics and in the Center for Alzheimer’s and Neurodegenerative Diseases at UT Southwestern, has been awarded $1.5 million from the National Institutes of Health (NIH) to determine the structure of amyloids, key proteins that have been tied to

UT Southwestern Medical Center is one of just 15 surgical centers in the world using next-generation augmented reality (AR) in the operating room for shoulder arthroplasty.

UT Southwestern researchers have identified a molecular pathway responsible for the spread of glioblastoma to surrounding tissue in the brain, as well as an existing drug that curbed tumor growth in animal models.

Protein complexes that play a critical role in launching an immune response assemble in droplets that form within the liquid environment in cells much like oil droplets in water, UT Southwestern scientists report in a new study.

COVID-19 impairs the function of the body’s microvascular system with an intensity that corresponds to the severity of disease, suggests a new study by an international consortium, including UT Southwestern Medical Center.

The National Academy of Sciences today elected four UT Southwestern Medical Center scientists in the fields of biophysics, cell biology, molecular biology, and stem cell biology into its membership, one of the highest honors for American scientists.

Scientists at UTSW have developed a technology that shuttles nanoparticles carrying gene editing and protein replacement tools to the specific tissues where they're needed.