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An increased concentration of the hormone leptin in fat cells is believed to be responsible for weight gain associated with antipsychotic drugs.

An extensive family of proteins that gives human skin mechanical strength also appears to organize molecular signals that control skin cell activity, a study led by UT Southwestern Medical Center researchers shows. Their findings, published in Developmental Cell, could lead to new ways to fight a

Patients with fibromyalgia and irritable bowel syndrome (IBS) who take multiple medications are more likely to develop severe drug intolerance than healthy patients, UT Southwestern Medical Center researchers reported.

A gene called Npas4, already known to play a key role in balancing excitatory and inhibitory inputs in brain cells, appears to also be a master timekeeper for the brain’s circadian clock, new research led by UT Southwestern scientists suggests.

A nanoparticle-based therapy developed by UT Southwestern Medical Center scientists stimulated an immune pathway that eradicated tumors in mouse models of various cancer types.

A molecule has demonstrated its ability to kill tumor cells and incite an immune response in preclinical models of small cell lung cancer (SCLC), according to UT Southwestern Medical Center researchers.

Automated external defibrillators (AEDs) are underutilized during cardiac arrest episodes despite laws in some states requiring their availability in high-risk areas such as athletic facilities, researchers at UT Southwestern Medical Center found. The devices can save lives by shocking the heart

UT Southwestern Medical Center is leading three multicenter clinical trials funded by the National Institute on Drug Abuse (NIDA) focused on potential treatments for methamphetamine or cocaine addiction.

The risk of dying while waiting for a liver transplant or having a transplant fail for patients with alcohol-associated liver diseases is higher among racial and ethnic minorities, according to UT Southwestern Medical Center researchers.

UT Southwestern Medical Center ranked fourth in the nation and No. 1 in Texas for commercializing new biomedical technologies, considered a critical step in bringing its laboratory discoveries into clinical practice.