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UT Southwestern researchers have discovered a mechanism that cells use to degrade microRNAs (miRNAs), genetic molecules that regulate the amounts of proteins in cells.

Researchers at UT Southwestern Medical Center have discovered sex-specific differences in how fat accumulates in muscle and bone, uncovering patterns that could inform new approaches to treating age-related diseases.

High-density lipoprotein (HDL), or “good” cholesterol, may play a vital role in conserving healthy brain matter in middle-aged adults, UT Southwestern Medical Center researchers report.

People with Type 2 diabetes had significantly fewer heart attacks, strokes, heart failures, and deaths from cardiovascular disease when their blood pressure was lower than the current standard goal, a UT Southwestern Medical Center researcher and his colleagues found.

A team led by UT Southwestern scientists has discovered a mechanism that promotes metastasis in pancreatic, breast, and potentially other cancers along with a new druggable therapeutic target based on this mechanism to block metastases.

A team led by UT Southwestern Medical Center researchers has identified a key mechanism responsible for endosomal recycling in cells, a process critical to human health. Their findings, published in Nature Communications, answer a fundamental question in cell biology and could lead to therapies for

A study led by a researcher at UT Southwestern Medical Center shows a national initiative significantly improved stroke outcomes for millions of patients over its first 20 years, enhancing quality of care and consistency at more than 2,800 U.S. hospitals including UTSW.

Failure of human pluripotent stem cells (PSCs) to survive when grown with the PSCs of distantly related species occurs because of an innate immune reaction in the nonhuman cells, a study led by UT Southwestern Medical Center researchers suggests.

– The STING protein, known for helping cells fight viral infections by generating inflammation, also appears to function as a quality control sensor for organelles that serve as cellular waste disposal systems, UT Southwestern Medical Center researchers found. Their study, published in Molecular

Using a powerful microscopy technique, a team led by researchers at UT Southwestern Medical Center has gained insights into how the body uses vitamin K, an essential nutrient that plays a pivotal role in blood clotting and other physiological functions.