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Researchers at UT Southwestern Medical Center have discovered how a bacterium that infects people after they eat raw or undercooked shellfish creates syringe-like structures to inject its toxins into intestinal cells.

The good bacteria that live in the guts of mammals program the metabolic rhythms that govern the body’s absorption of dietary fat.

Researchers at UT Southwestern Medical Center have discovered how healthy bacteria can escape the intestine, travel to lymph nodes and cancerous tumors elsewhere in the body, and boost the effectiveness of certain immunotherapy drugs.

In humans, virtually every cell stores fat. However, patients with a rare condition called congenital lipodystrophy, which is often diagnosed in childhood, cannot properly store fat, which accumulates in the body’s organs and increases the risk of early death from heart or liver disease.

Cell membrane protrusions called blebs that typically signify the end of life for healthy cells do the opposite for melanoma cells, activating processes in these cells that help them to survive and spread, a UT Southwestern study suggests.

The COVID-19 pandemic is having a detrimental impact on substance use, mental health, and weight-related health behaviors among people with obesity, according to a new study by researchers at UT Southwestern and the UTHealth School of Public Health.

UT Southwestern Medical Center researchers have discovered a method cells use to turn genes on and off that involves portions of proteins whose function has long been a mystery.

Lorena Saelices Gomez, Ph.D., Assistant Professor of Biophysics and in the Center for Alzheimer’s and Neurodegenerative Diseases at UT Southwestern, has been awarded $1.5 million from the National Institutes of Health (NIH) to determine the structure of amyloids, key proteins that have been tied to

Only 22% of Texas patients with early-stage pancreatic cancer received standard-of-care surgery to remove their tumors, researchers at UT Southwestern Medical Center report in a new study.

The National Academy of Sciences today elected four UT Southwestern Medical Center scientists in the fields of biophysics, cell biology, molecular biology, and stem cell biology into its membership, one of the highest honors for American scientists.