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Immune protein STING key for repairing, generating lysosomes: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/april-immune-protein-sting-key.html

– The STING protein, known for helping cells fight viral infections by generating inflammation, also appears to function as a quality control sensor for organelles that serve as cellular waste disposal systems, UT Southwestern Medical Center researchers found. Their study, published in Molecular

Presurgical radiation may curb pancreatic cancer recurrence: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/july-presurgical-radiation-pancreatic-cancer.html

Adding targeted radiation to chemotherapy prior to surgery may offer better control of pancreatic tumors – potentially reducing the rate of recurrence after treatment, according to a new study from UT Southwestern Medical Center. Published in Clinical Cancer Research, the novel study offers evidence

Hormone may hold key to longer life, improved metabolic health : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/july-hormone-improved-metabolic-health.html

Fat cells genetically altered to overproduce a hormone called FGF21 resulted in improved metabolic health and an extended lifespan in mice that were fed a high-fat diet, UT Southwestern Medical Center researchers report. The findings, published in Cell Metabolism, could lead to new interventions

Heat-related illnesses among children on the rise : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/july-heat-related-illnesses-children.html

Higher summer temperatures are resulting in more children seeking emergency care for heat-related illnesses, with nearly 1 in 5 needing hospitalization, according to new research from UT Southwestern Medical Center published in Academic Pediatrics.

Children’s Research Institute at UT Southwestern scientists discover ancient viral DNA activates blood cell production during pregnancy, after bleeding: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/oct-cri-utsw-ancient-viral-dna.html

Ancient viral remnants in the human genome are activated during pregnancy and after significant bleeding in order to increase blood cell production, an important step toward defining the purpose of “junk DNA” in humans, according to new research from Children’s Medical Center Research Institute at

Combination therapy slows cognitive decline, research shows: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/oct-combination-therapy-cognitive-decline.html

A novel combination therapy slowed cognitive decline in elderly patients with a history of depression – a major risk factor for developing Alzheimer’s and other forms of dementia, a study led by UT Southwestern Medical Center’s new Chair and Professor of Psychiatry found.

UTSW’s Simmons Cancer Center awarded more than $11.5 million in CPRIT funding: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/sept-scc-awarded-cprit-funding.html

Eight scientists and physicians in the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern have been awarded more than $11.5 million in grants from the Cancer Prevention and Research Institute of Texas (CPRIT) to support the state’s fight against cancer.

How sex and age shape fat patterns in muscles and bones: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/jan-sex-and-age-shape-fat-patterns.html

Researchers at UT Southwestern Medical Center have discovered sex-specific differences in how fat accumulates in muscle and bone, uncovering patterns that could inform new approaches to treating age-related diseases.

‘Good’ cholesterol may protect against brain atrophy, dementia: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/jan-good-greater-gray-matter-volume.html

High-density lipoprotein (HDL), or “good” cholesterol, may play a vital role in conserving healthy brain matter in middle-aged adults, UT Southwestern Medical Center researchers report.

Children’s Medical Center Dallas seeks community participation in trauma research study to investigate treatment strategies for critically injured children : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/sept-cmcd-trauma-research-study.html

Bleeding is the most common cause of preventable death after injury. Researchers at Children’s Medical Center Dallas are seeking community consultation for possible future participation from parents and legal guardians in a study that will compare two resuscitation treatments (whole blood versus