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A protein identified by researchers at UT Southwestern Medical Center may drive resistance to immune checkpoint inhibitors, a widely used form of immunotherapy to treat cancer.

– The STING protein, known for helping cells fight viral infections by generating inflammation, also appears to function as a quality control sensor for organelles that serve as cellular waste disposal systems, UT Southwestern Medical Center researchers found. Their study, published in Molecular

Survival rates for out-of-hospital cardiac arrest (OHCA) fell during the early years of the COVID-19 pandemic, with Black and Hispanic patients experiencing larger decreases in survival, according to a study by UT Southwestern Medical Center researchers published in Resuscitation.

High levels of physical activity may mitigate brain loss in adults and help maintain long-term cognitive health, researchers at UT Southwestern Medical Center report in a study published in the Journal of Applied Physiology.

The role of the microbiome in intestinal and systemic health has garnered close attention among researchers for many years. Now evidence is mounting that this collection of microorganisms in the human gut can also impact a person’s neurological and emotional health.

Patients who develop lupus as children will eventually shift to adult rheumatology care. In a unique collaboration between rheumatologists at UT Southwestern and Children’s Health, investigators conducted a qualitative study, which showed that patients’ health literacy and taking an active role in

Eight scientists and physicians in the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern have been awarded more than $11.5 million in grants from the Cancer Prevention and Research Institute of Texas (CPRIT) to support the state’s fight against cancer.

A person’s IQ during high school is predictive of alcohol consumption later in life, according to a study by UT Southwestern Medical Center researchers published in Alcohol and Alcoholism.

A drug approved for diabetes has now been shown to also help patients with diabetes lose on average 10 percent of their body weight, UT Southwestern reports in a landmark international study.

Fat cells, or adipocytes, that grow in close proximity to breast cancers can shift into other cell types that promote tumor growth, a new study by UT Southwestern researchers suggests.