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Kidney cancer drug shows promise against dangerous calcium imbalance caused by tumors: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/oct-kidney-cancer-drug.html

Elevated calcium levels in the blood – a complication of kidney cancers known as hypercalcemia – may be successfully treated with a class of medications called HIF-2 inhibitors developed by UT Southwestern Medical Center, a new study shows. The findings, published in Cancer Discovery by a team at

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UTSW scientists identify mechanism crucial for COVID-19 virus replication: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2022/august-covid-19-virus-replication.html

A team led by UT Southwestern researchers has identified how SARS-CoV-2, the virus that causes COVID-19, builds a structure called the RNA cap that’s critical for successful viral replication.

UTSW Pharmacologist James Collins receives 2023 TAMEST Edith and Peter O’Donnell Award: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2023/january-tamest-collins.html

James Collins III, Ph.D., Associate Professor of Pharmacology at UT Southwestern Medical Center, will receive the 2023 Edith and Peter O’Donnell Award in Biological Sciences from The Academy of Medicine, Engineering and Science of Texas (TAMEST) for broadening understanding of schistosomiasis, a

Researchers identify protein produced after stroke that triggers neurodegeneration: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2021/neurodegeneration.html

Researchers with the Peter O’Donnell Jr. Brain Institute at UT Southwestern have identified a new protein implicated in cell death that provides a potential therapeutic target that could prevent or delay the progress of neurodegenerative diseases following a stroke.

Children’s Research Institute scientists uncover unique pathway tumors use to acquire antioxidant lipids: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/june-cri-utsw-pathway-tumors-antioxidant-lipids.html

Scientists have discovered tumors can tap a nontraditional pathway to acquire lipoproteins – molecules that transport fat in blood – which enriches cancer cells with an antioxidant shield to survive stress, according to new research from Children’s Medical Center Research Institute at UT

Artificial intelligence predicts kidney cancer therapy response: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/april-ai-kidney-cancer-therapy.html

An artificial intelligence (AI)-based model developed by UT Southwestern Medical Center researchers can accurately predict which kidney cancer patients will benefit from anti-angiogenic therapy, a class of treatments that’s only effective in some cases.

FDA approval of belzutifan culminates 25-year journey at UTSW from gene discovery to a first-in-class drug: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2021/fda-approval-belzutifan.html

A first-in-kind kidney cancer drug developed from laboratory and translational studies conducted at UT Southwestern Medical Center received approval from the Food and Drug Administration, providing a new treatment for patients with familial kidney cancer.

$25 million donation from Hamon Charitable Foundation will help UT Southwestern, Children’s Health develop joint pediatric campus: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/sept-hamon-charitable-foundation-donation.html

UT Southwestern Medical Center and Children's HealthSM announced a $25 million gift from the Hamon Charitable Foundation in support of the $5 billion transformative pediatric campus to be built in Dallas’ Southwestern Medical District across from UTSW’s William P. Clements Jr. University Hospital.

Over its first 10 years, Clements University Hospital sparked a clinical transformation at UT Southwestern : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/dec-cuh-clinical-transformation.html

When William P. Clements Jr. University Hospital (CUH) opened on Dec. 6, 2014, it established a new level of care in North Texas, where patients could receive the most advanced treatments for both common and complex conditions in a truly healing environment.