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High-density lipoprotein (HDL), or “good” cholesterol, may play a vital role in conserving healthy brain matter in middle-aged adults, UT Southwestern Medical Center researchers report.

A far shorter, simpler, and less toxic treatment protocol for patients with triple-negative breast cancer produced outcomes similar to the current standard of care, a clinical trial co-led by a UT Southwestern Medical Center researcher shows.

A team led by UT Southwestern scientists has discovered a mechanism that promotes metastasis in pancreatic, breast, and potentially other cancers along with a new druggable therapeutic target based on this mechanism to block metastases.

UT Southwestern Medical Center is part of a major undertaking that will bring together more than 40 scientists, doctors, and industry experts handpicked from around the country to make vision-restoring whole eye transplants a reality.

Researchers at UT Southwestern Medical Center have discovered sex-specific differences in how fat accumulates in muscle and bone, uncovering patterns that could inform new approaches to treating age-related diseases.

A team led by UT Southwestern Medical Center researchers has identified a key mechanism responsible for endosomal recycling in cells, a process critical to human health. Their findings, published in Nature Communications, answer a fundamental question in cell biology and could lead to therapies for

UT Southwestern Medical Center is the No. 1 hospital in Dallas-Fort Worth – the nation’s fourth-largest metro area – for the sixth consecutive year and ranks among the top hospitals nationally in nine specialties ranging from brain to heart to cancer care.

UT Southwestern Medical Center has established the Beth Levine, M.D. Prize in Autophagy Research, an annual award and lecture for exceptional scientists who have made significant contributions to the field of autophagy.

Researchers at UT Southwestern Medical Center have discovered an intracellular mechanism that converts protective intestinal cells into disease-driving pathogenic cells, a finding that could lead to improved treatments for patients with inflammatory bowel disease (IBD).

A gene previously linked to autism spectrum disorder (ASD) by UT Southwestern Medical Center researchers appears to play an important role in steering cells in the brain’s hippocampus toward their ultimate identities, the same team reported in a new study. The findings, published in Science Advances