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Malaria, responsible for hundreds of thousands of deaths each year worldwide, is caused by a parasite transmitted through the salivary glands of female Anopheles mosquitoes. Understanding the biology of these tissues is critical to developing new treatments for the disease, found mostly in tropical

Adults who developed severe obesity before the age of 18 were nearly three times more likely than those who developed the condition later to be subjected to severe experienced weight stigma (EWS), a study led by UT Southwestern Medical Center researchers shows.

A new study by UT Southwestern scientists indicates that an enzyme called protein phosphatase 2 (PP2A) appears to be a major driver of preeclampsia, a dangerous pregnancy complication characterized by the development of high blood pressure and excess protein in the urine.

Two studies led by UT Southwestern researchers shed light on the biology and potential vulnerabilities of schistosomes – parasitic flatworms that cause the little-known tropical disease schistosomiasis.

Millions of children have food allergies, many of which can cause severe illness or death. In a study published in the New England Journal of Medicine, a team of researchers, including those from UT Southwestern, shows in a phase three clinical trial that an antibody-based therapy called omalizumab

Using UT Southwestern’s Cryo-Electron Microscopy Facility, researchers have captured images of an enzyme for Wnt lipidation, which is pivotal to human development and cancer and crucial for Wnt signaling activation.

An experimental device known as a bionic pancreas kept blood sugar levels within normal ranges more effectively than standard-of-care glucose management among patients with Type 1 diabetes in a multicenter trial conducted partly at UT Southwestern.

Fusing the neck’s top two vertebrae can prevent repeat strokes in children with bow hunter syndrome, a rare condition that affects a handful of U.S. pediatric patients each year, UT Southwestern researchers suggest in a recent study.

Ralph DeBerardinis, M.D., Ph.D., a professor at the Children’s Medical Center Research Institute at UT Southwestern (CRI), has been elected to the National Academy of Medicine (NAM), one of the highest honors in the fields of health and medicine.

A team led by UT Southwestern researchers has identified brain circuitry that plays a key role in the dysfunctional social, repetitive, and inflexible behavioral differences that characterize autism spectrum disorders (ASD).