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UT Southwestern biochemist Zhijian “James” Chen, Ph.D., famously identified the cGAS enzyme pathway that alerts the human immune system to disease-causing invaders like viruses. Since then, researchers have found that cGAS signaling is an ancient, conserved defense strategy stretching from bacteria

Led by two UT Southwestern physicians, a team of researchers from 15 U.S. medical centers has performed the first analysis of a potentially game-changing drug to treat upper urinary tract urothelial cancers.

Summertime means lots of opportunities for fun in the sun. But this year’s high temperatures also bring an increased risk of dehydration that can cause urinary tract infections (UTIs), said Maude Carmel, M.D., Associate Professor of Urology at UT Southwestern Medical Center.

Vaginal progesterone, a hormone treatment considered the standard of care for preventing preterm birth in at-risk pregnant women, may not be effective, according to UT Southwestern researchers.

A clinical trial is only as powerful as its participants. For years, researchers have struggled to fill clinical trials and enroll sufficiently diverse groups of patients for results to reflect the broader population, in part because of stringent guidelines on who can participate.

A single protein can reverse the developmental clock on adult brain cells called astrocytes, morphing them into stem-like cells that produce neurons and other cell types, UT Southwestern researchers report in a PNAS study.

When McKinney real estate developer John Hill was 35, his father died of prostate cancer. The elder Mr. Hill had undergone surgery to remove his prostate a few years earlier, but the cancer had already spread.

UT Southwestern Medical Center is one of seven health systems in the nation being recognized for its leadership development initiatives, the latest in a series of national and regional employer honors.

UT Southwestern Medical Center has received exemplar status by the Nurses Improving Care for Healthsystem Elders (NICHE).

A pregnant mother who tested positive for COVID-19 transmitted the virus causing the disease to her prematurely born baby, UT Southwestern physicians report. Both were treated and recovered.