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The importance of increasing the number of Black male doctors in the United States will be the subject of a virtual panel discussion at UT Southwestern in advance of the release of a documentary on the issue.

In a move that will increase access and efficiency of clinical trials for patients with sickle cell disease.

A study led by UT Southwestern and Children’s Health researchers defines parameters for the number of white blood cells that must be present in children’s urine at different concentrations to suggest a urinary tract infection (UTI).

A potential treatment for polycystic kidney disease – a genetic disorder that causes the kidneys to swell with multiple cysts and can eventually lead to organ failure – has shown promising results in animal testing.

Researchers at Children’s Medical Center Research Institute at UT Southwestern (CRI) have uncovered why certain melanoma cells are more likely to spread through the body.

Eliminating a single gene can turn exhausted cancer-fighting immune cells known as CD8+ T cells back into refreshed soldiers that can continue to battle malignant tumors, a new study led by UT Southwestern researchers suggests.

About half of all tumors have mutations of the gene p53, normally responsible for warding off cancer. Now, UT Southwestern scientists have discovered a new role for p53 in its fight against tumors: preventing retrotransposons, or “jumping genes,” from hopping around the human genome.

A new type of CAR T-cell therapy more than triples the expected length of remission for multiple myeloma patients who have relapsed several times, according to an international clinical trial with UT Southwestern as the lead enrolling site.

Immunotherapy drugs that target a protein called programmed death ligand 1 (PD-L1) on the surface of cancer cells have quickly become a mainstay to treat many forms of cancer, often with dramatic results.

UT Southwestern researchers have determined how circulating “bad cholesterol” enters artery walls to cause the plaque that narrows the blood vessels and leads to heart attacks and strokes.