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While the amazing regenerative power of the liver has been known since ancient times, the cells responsible for maintaining and replenishing the liver have remained a mystery.

A potential treatment for polycystic kidney disease – a genetic disorder that causes the kidneys to swell with multiple cysts and can eventually lead to organ failure – has shown promising results in animal testing.

UT Southwestern will lead a multisite initiative funded by the National Cancer Institute (NCI) to identify biomarkers to improve risk assessment and early detection of hepatocellular cancer (HCC), the most common form of liver cancer, among patients with cirrhosis.

UT Southwestern Medical Center researchers have identified a compound that selectively eliminates cancer cells while sparing immune cells in a form of cell death known as ferroptosis.

Triptans, a commonly prescribed class of migraine drugs, may also be useful in treating obesity, a new study by scientists at UT Southwestern suggests.

By examining which genes were turned on and off in a mix of cell types from breast cancer biopsies, a team led by UT Southwestern Medical Center researchers developed a tool that can accurately predict which patients with breast cancer will respond to immunotherapies.

Liver cells have a vital metabolic inflexibility during regeneration to starve dysfunctional cells and keep damage from spreading, according to new research from Children’s Medical Center Research Institute at UT Southwestern (CRI) published in Science.

A new study focused on the gene tied to a rare form of autism spectrum disorder (ASD) called FOXP1 syndrome offers hope that gene therapy might be able to help patients with this condition.

A team led by researchers at UT Southwestern Medical Center developed deep learning models to identify a simple set of rules that govern the activity of promoters – regions of DNA that initiate the process by which genes produce proteins.

More than 1,000 residents, business owners, and regional leaders gathered Saturday at the community celebration for the opening of UT Southwestern Medical Center at RedBird, the largest of its regional campuses and the first to bring academic medicine to the booming southern Dallas region.