The Translational Research Imaging (TRI) laboratory is in the second floor of Clements building, next to the Rogers MRI Center and the Advanced Imaging Research Center (AIRC) and has the following computing capabilities:
- iMac running Osirix (64 bit in native Mac-OSX) configured as a DICOM node for the MR scanners.
- A PC running Aperio System for online viewing of pathology slides
- Office, Image J, Matlab, Photoshop
The computers in the TRI Lab are remotely connected to a the Image Processing Laboratory, which includes several workstations with MR and MR spectroscopy (MRS) analysis; software packages (Remcom and HFSS) for radiofrequency (RF) coil simulations at 3T and 7T; and advanced MR image reconstruction development using the latest version of Recon software environment (Recon2) from Philips Healthcare.
A dedicated Picture Archive and Communication Systems (PACS) for research (iPACS) allows for secure, web-based access of both clinical and pre-clinical research imaging data. iPACS is completely integrated with VivoQuant™, a software solution that provides investigators with access, viewing capabilities, and analysis of their data.
Radiology Translational Research (RTR) MRI
A new Philips 3T Ingenia MRI scanner (Digital architecture) was installed in January 2014 to facilitate technical development, protocol optimization, and translational research in Radiology with particular emphasis on developing and validating new quantitative MR techniques for physiologic characterization of disease. This system is also equipped with High-intensity Focused Ultrasound (HIFU) capabilities for clinical/preclinical ablation of tumors and targeted delivery of chemotherapy using temperature-sensitive liposomes. The MR suite and patient holding area are equipped with medical gases and MR-compatible physiologic monitoring to conduct both imaging and therapeutic MR experiments.
The Translational Research Imaging (TRI) laboratory focuses on developing and implementing new MRI technologies in the clinic. Emphasis is made to incorporate new MRI technologies into clinical protocols.
There are 9 full body MR scanners utilized for both clinical and research studies throughout the UTSW Campus: 3 Philips 3T Ingenia (all three with Digital architecture and 1 dedicated for research purposes in the NE building, described above), 2 Philips 3T Achieva TX scanners (both with parallel transmit); 1 Philips 1.5T Ingenia (Digital architecture), and 3 other 1.5T scanners: 2 Philips Achieva (16 channels) and 1 Siemens Avanto. An additional Siemens 3T Prisma MRI was installed in September 2015 for imaging of in-patients in the new Zale Lipshy Pavilion—William P. Clements Jr. University Hospital.
Clinical translational research is facilitated by the Radiology Clinical Trials Office (RCTO)