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Understanding mechanisms
of tumorigenesis
We investigate mechanisms of tumor initiation, progression, and metastasis using molecular and biochemical studies and animal models.
Understanding mechanisms
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Novel cancer therapeutics
We apply insights from molecular and genetic studies towards the development of new therapies for lung cancer and other tumor types.
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Functional genetic approaches
We perform unbiased genetic screens to uncover new therapeutic targets for cancer.
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Investigating new mechanisms of immune checkpoint regulation
Integrated stress response-dependent translation of PD-L1 in lung cancer, leading to suppression of anti-tumor immunity. Image depicts PD-L1 protein (left) engaging the T-cell PD-1 receptor (right).
Research
Meet the PI
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