Amyloids are ordered protein assemblies that can transmit biological information and cause disease.
We focus on neurodegen-
erative diseases linked to amyloid protein accumulation with the goal of developing mechanism-based diagnosis and therapy.
We are studying neurodegeneration from the standpoint of prion biology and protein aggregation. All major neurodegenerative diseases are relentlessly progressive, and virtually all are linked to the accumulation of protein amyloids.