New research led by Ralph DeBerardinis, M.D., Ph.D., Director of the Eugene McDermott Center for Human Growth and Development and a Professor in Children’s Medical Center Research Institute at UT Southwestern (CRI), shows that metastatic kidney cancers depend on mitochondria – tiny power plants in cells – for energy, unlike kidney tumors that stay in place. More than 80 UTSW patients were studied to understand how these cancers use sugar and nutrients from the blood. This discovery could lead to new ways to treat advanced kidney cancer. Dr. DeBerardinis is also a Professor of Pediatrics at UTSW and a member of the Harold C. Simmons Comprehensive Cancer Center.

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