A journey to discovery Published on: October 25, 2018 By: Staff Reports Tags: Video Research Share: Share on Facebook Share on Twitter Share on Pinterest Share on Google Plus Share on LinkedIn UT Southwestern biochemist Dr. Zhijian “James” Chen was named winner of the prestigious 2019 Breakthrough Prize in Life Sciences for his discovery of the cGAS enzyme that launches the body’s immune defense against infections and cancers. That enzyme patrols the cell’s interior and triggers the immune system in response to DNA.