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Study sheds new light on urinary tract infections in postmenopausal women

Urinary Tract NR - Header
From left, Drs. Kim Orth, Nicole De Nisco and Philippe Zimmern look over samples of bacteria from their study that found several species of bacterial invaded bladder walls in recurrent urinary tract infections.
Graphic illustrating inflamation from a Urinary Tract infection
The study showed that in recurrent urinary tract infections, several species of bacteria can invade bladder walls, leading to a vicious cycle of chronic inflammation and infection.

A UT Southwestern study suggests why urinary tract infections (UTIs) have such a high recurrence rate in postmenopausal women – several species of bacteria can invade the bladder walls.

UTI treatment is the most common reason for antibiotic prescriptions in older adults. Because of the prevalence of UTIs, the societal impact is high and treatment costs billions of dollars annually.

Recurrent UTI (RUTI) reduces quality of life, places a significant burden on the health care system, and contributes to antimicrobial resistance, said Dr. Kim Orth, Professor of Molecular Biology and Biochemistry at UTSW and senior author of the study, published in the Journal of Molecular Biology.

Read the full story in the UT Southwestern Newsroom.

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