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Stimulating fat cells with GIP receptor has potential to treat obesity

Stimulating fat cells with GIP receptor has potential to treat obesity

Obese mice whose fat cells were genetically altered to produce an increased amount of the glucose-dependent insulinotropic polypeptide receptor (GIPR) lost more than a third of their body weight through a mechanism that burns energy, UT Southwestern Medical Center researchers report in a new study

‘Good’ cholesterol may protect against brain atrophy, dementia

‘Good’ cholesterol may protect against brain atrophy, dementia

High-density lipoprotein (HDL), or “good” cholesterol, may play a vital role in conserving healthy brain matter in middle-aged adults, UT Southwestern Medical Center researchers report

CRI scientists link hematopoietic cell transplant deaths to beta-blocker use

CRI scientists link hematopoietic cell transplant deaths to beta-blocker use

Patients can die if they take certain previously prescribed beta-blockers during a hematopoietic cell transplant due to suppressed signals from nerves that promote bone marrow regeneration

UTSW scientists identify cancer-suppressing genetic mutation

UTSW scientists identify cancer-suppressing genetic mutation

UT Southwestern Medical Center researchers identified a genetic mutation that slows the growth of melanoma and potentially other cancers by harnessing the power of the immune system. Their findings, published in the Journal of Experimental Medicine, could lead to new treatments that improve outcomes

New findings expand genetic knowledge of autism underpinnings

New findings expand genetic knowledge of autism underpinnings

Hundreds of novel genetic variants across an ancestrally diverse cohort of 195 families, including 222 people with autism spectrum disorder (ASD), have been identified by researchers at UT Southwestern Medical Center, expanding the catalog of known mutations associated with ASD

CRI’s Gerta Hoxhaj, Ph.D., named TAMEST 2025 Mary Beth Maddox Award and Lectureship recipient

CRI’s Gerta Hoxhaj, Ph.D., named TAMEST 2025 Mary Beth Maddox Award and Lectureship recipient

Gerta Hoxhaj, Ph.D., Assistant Professor in Children’s Medical Center Research Institute at UT Southwestern (CRI), is the recipient of the Texas Academy of Medicine, Engineering, Science and Technology (TAMEST) 2025 Mary Beth Maddox Award and Lectureship for her research in cancer metabolism

Genetic testing moving into the mainstream, UTSW study finds

Genetic testing moving into the mainstream, UTSW study finds

Genetic testing, which has expanded in recent years with advances in technology and the development of consumer products, is on a path to widespread acceptance in the U.S., researchers at UT Southwestern Medical Center found

Healthy eating habits to carry you through the holidays

Healthy eating habits to carry you through the holidays

This season of office parties and extravagant meals is filled with tempting treats that can make it difficult to reach your health goals

UTSW Research: Python guts, emergency room visits, and more

UTSW Research: Python guts, emergency room visits, and more

Oncology programs have sought to decrease visits by cancer patients to a hospital emergency department (ED) by offering resources such as 24/7 phone triage lines and urgent care clinics. However, these tend to be underutilized

Innovative surgery preserves limb growth for childhood bone cancer patients

Innovative surgery preserves limb growth for childhood bone cancer patients

– Arlette Chavez was a typical 3-year-old who loved jumping on the bed, riding her bike, and playing tag, said her mother, Lesly Rivera. When this active preschooler started complaining of pain in her left arm, Ms. Rivera and her husband, Carlos Chavez, weren’t overly concerned – it was probably a