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The Cecil H. and Ida Green Center for Reproductive Biology Sciences addresses fundamental and applied questions related to reproduction, development, and gene regulation.

50th Anniversary

The Green Center celebrates its 50th anniversary in 2024! Check out our 50 years of history and in a Center Times news article.

Cecil H. and Ida Green Center Celebrates 50th Anniversary
“The Green Center is really the nexus of gene regulation study on campus.”

Events

We held several celebratory events this year:

We also congratulate the Kraus Lab on its 25th anniversary in 2024!

Mission

To promote and support leading-edge, integrative, and collaborative basic research in female reproductive biology, with a focus on signaling, gene regulation, and genome function.

Approximately 100 members of the Green Center lined up on the stairs in front of Pegasus Park
2023 Green Center for Reproductive Biology Sciences Retreat

Overview

A panel of 6 photos depicting egg cells, sperm cells, sperm fertilizing an egg, a blastocyst, a human fetus, and a newborn human baby
The Green Center conducts research in reproductive biology at various scales, from individual gametes through fertilization, embryonic and fetal development, and parturition.

The Cecil H. and Ida Green Center for Reproductive Biology Sciences is a department-level endowed basic science research center at UT Southwestern Medical Center under the direction of Dr. W. Lee Kraus, Professor and Director, Cecil H. and Ida Green Center for Reproductive Biology Sciences, Professor and Vice Chair for Basic Sciences in the Department of Obstetrics and Gynecology, Professor in the Department of Pharmacology, and the Cecil H. and Ida Green Distinguished Chair in Reproductive Biology Sciences.

Situated primarily in the Harry S. Moss Clinical Science Building (J) on the South Campus, the Green Center is a state-of-the-art research facility housing University research labs as well as molecular biology and computational genomic cores for use by members of the Green Center.

The Green Center faculty includes faculty from the Department of Obstetrics and Gynecology, along with additional members from a variety of other departments across campus. Each work in diverse areas of reproduction, development, gene regulation, and genomics. As a result, the Green Center plays a key role in promoting the study of reproduction, development, gene regulation, and genomics at UTSW.

The Science of the Green Center

A panel of 4 pictures depicting a stained cell, condensed chromatin, and 2 illustrations of DNA with associated proteins
The Green Center conducts research in gene regulation, including chromatin structure, epigenetics, genome organization, and RNA biology.

The research faculty members of the Green Center are addressing fundamental and applied questions related to reproductive biology in a broad sense, as well as related areas relevant to reproductive biology.

Classical reproductive biology:

  • Oocyte maturation
  • Fertilization
  • Development
  • Pregnancy
  • Parturition

Related areas relevant to reproductive biology:

  • Endocrinology
  • Oncology
  • Stem cells
  • Metabolism
  • Inflammation
  • Immunity

The focus of the research in the Green Center is on nuclear regulation, but includes other aspects of cellular regulation as well. Key research areas include:

  • Chromatin structure and gene regulation
  • Epigenetics
  • Nuclear endpoints of cellular signaling pathways
  • Genome organization and evolution
  • RNA Biology

Researchers in the Green Center use the tools of:

  • Biochemistry
  • Molecular biology
  • Structural biology
  • Animal models
  • Genomics
  • Proteomics
  • Bioinformatics
  • Computational biology