Cell and Molecular Biology Faculty

Research Interests: Mechanisms of membrane fusion; role of lipids in membrane trafficking; membrane vesiculation of dynamin

Research Interests: The intersection between human signal-transduction and bacterial pathogenesis; use of biochemical and cell biological analysis to define molecular mechanisms of microbial infectious disease

Research Interests: Signal transduction, Mitochondria function, Cell growth and proliferation, Cancer metabolism

Research Interests: Cell-cell fusion, actin cytoskeletal dynamics, muscle development and regeneration

Research Interests: Mechanisms of transcriptional regulation and epigenetic control; chromatin remodeling and histone tail modification; sumoylation and ubiquitination; functional interplay between oncoproteins and tumor suppressor proteins; general transcription factors and cofactors

Research Interests: Protein kinase cascades; MAP kinases; signal-transduction mechanisms

Research Interests: Germ cells, immunology, parasite biology, pathogenesis, regeneration, stem cells

Research Interests: Cell migration, survival, stress responses, cancer

Research Interests: Uncover mechanisms that modulate the cellular response to DSBs

Research Interests: Regulation of HMG-CoA reductase and sterol metabolism

Research Interests:

Research Interests: Mitochondria, cristae biogenesis, organelles, membrane organization, inter-organelle contacts

Research Interests: Intracellular sorting of newly synthesized proteins; organelle biogenesis and membrane structure and function; the yeast peroxisome as a model of organellar assembly

Research Interests: Molecular mechanisms of circadian rhythms and how they control metabolism

Research Interests: Molecular mechanisms of membrane sculpting; formation and dynamics of inter-organelle membrane contact sites (MCSs) in human health and disease

Research Interests: Molecular signaling processes in cardiac hypertrophy and failure; mechanisms of structural, functional, and electrophysiological remodeling, using genetic and surgical mice models

Research Interests: Hepatic steatosis; lipid metabolism

Research Interests: Cytokine receptor; signal transduction; hematopoiesis; structure-function analysis of protein; cancer

Research Interests: Renal metabolism; inflammation and sepsis; acute kidney injury

Research Interests:  Cancer Cachexia, Obesity, Adipocyte biology

Research Interests: Physiology of nuclear receptors

Research Interests: Structural and biochemical characterization of cholesterol biosynthesis, transport and signaling

Research Interests: Spatial and temporal regulation of cellular signaling events; mechanisms and physiological roles of store-operated calcium signaling

Research Interests:Wound healing, tissue repair and regeneration, innate immunity, inflammation and cancer

Research Interests:Mechanobiology, ion channels, immune cells, human genetics, disease, cell communication

Research Interests: Parturition (the process of labor); cervical ripening; male and female reproductive biology

Research Interests: Post-transcriptional gene regulation and signaling in the immune and nervous system

Research Interests: Mechanism of nuclear hormone receptor action; role of retinoids in cancer; transcriptional regulation of lipid metabolism

Research Interests: Regulation of cell-cell adhesion during tubule and glomerular formation and in polycystic kidney disease

Research Interests: Ubiquitylation, Protein quality control, Gene expression, stem cells, cancer, neurodegeneration

Research Interests: Molecular genetics of human cancer; growth factors and signal transduction in human tumors

Research Interests: Molecular mechanical force field development; virtual screenings for drug lead identification; Molecular dynamics simulations of protein folding and drug delivery; and rational protein design

Research Interests: Transcriptional mechanisms that orchestrate formation and function of the cardiac conduction system

Research Interests: Immunogenic Cell Death, Necroptosis Signaling, Anti-tumor Immunity, Immunotherapy

Research Interests: Epidermal remodeling during wound healing, Molecular basis of skin architecture

Research Interests: Three-dimensional structures and functions of organelles and macromolecular complexes, with special emphasis on cytoskeletal assemblies and molecular motors

Research Interests: Uncovering insights into GPCR signal transduction and its physiological function in various metabolic disease models

Research Interests: Developmental Biology, Cancer Biology, RNA Regulatory Programs and Transcriptional and Post-transcriptional Feedback Loops

Research Interests: Evolution of signaling pathways, gene regulation, growth control, signal transduction, tumor suppressor, genes and oncogenes

Research Interests: Metabolism, tyrosine kinase signaling, vascular biology, kidney biology, aging

Research Interests:Cytoskeleton, Actin, Microtubules, Developmental Biology, Evolution, Fertility, Cancer, Structural Biology

Research Interests: Biogenesis of the Golgi apparatus

Research Interests: Gene therapy, Rare neurodevelopmental disorders, Rett syndrome (RTT), Regulatory elements

Research Interests: Sensory transduction in Drosophila melanogaster

Research Interests: Se!O, AMPylation, mitochondria, selenoproteins, oxidative stress, reactive oxygen species, selenocysteine

Research Interests: Kinases in the secretory pathway and the extracellular space; secreted protein and peptide hormone phosphorylation; CRISPR/Cas9 genome editing

Research Interests: Vascular biology; oxidant biochemistry; signal transduction; acute lung injury

Research Interests: Heart failure, Atrial fibrillation

Research Interests: Forward genetics, mucosal immunology; host-microbe interactions; innate immunity; vesicle trafficking

Research Interests: Membrane protein trafficking and function; autophagy and its developmental roles; organelle biogenesis and communication

Research Interests: The function of molecular factor and transcription regulation in skeletal disease and bone cancer

Research Interests: Proteolytic mechanisms in cell fate, signaling and gene expression. Roles of caspases, E3 ubiquitin ligases and MAPK signaling in development and stress responses.

Research Interests: Cellular and molecular pathogenesis of leishmaniasis and other parasitic infections; host-pathogen interactions; development of novel antiparasitics

Research Interests: Understand oocyte ageing, embryogenesis and cancer onset by use of live-cell microscopy, nano-rheology and synthetic biology

Research Interests: Harnessing stem cell derived interspecies chimeras for studying developmental biology in an evolutionary context, probing species’ specific traits, and uncovering molecular basis of species barriers

Research Interests: Geranylgeranylation and HCV replication; regulation of geranylgeranyl lipid homeostasis; regulated intramembrane proteolysis

Research Interests: Biochemistry of signal transduction, gene regulation, and membrane protein complexes; molecular and cellular mechanisms of neurogenesis, neuroplasticity, and neurodegeneration

Research Interests: Mechanism of Bi-d\Directional Communication between Sympathetic Neurons and Adipocytes, Role of Mitochondria in Adipose Thermogenesis and Neurogenesis, Novel Pathways Regulating Adipose Thermogenesis

Research Interests: Diabetes, obesity, metabolic imaging, and tracer techniques

Research Interests: Gene regulation, molecular mechanisms of eukaryotic transcription, chromatin modifying and remodeling enzymes

Research Interests: Cholesterol and fat metabolism

Research Interests: Molecular mechanisms of heart disease, cellular pathways involved in cardiac growth, function and response to stress

Research Interests: Genetics and biochemistry of lipoprotein and cholesterol metabolism; cell-surface receptor function; regulation of gene expression

Research Interests: Breast cancer, targeted therapy, drug resistance, precision medicine, kinase signaling, oncogenes

Research Interests: Adipose tissue, obesity, iron, macrophages, T cell memory, weight cycling

Research Interests: G protein-mediated signaling

Research Interests: Mechanisms for signal transduction through the actin cytoskeleton